The NED foundation experience: A model of global neurosurgery.

Introduction: The Neurosurgery Education and Development (NED) Foundation (NEDF) started the development of local neurosurgical practice in Zanzibar (Tanzania) in 2008. More than a decade later, multiple actions with humanitarian purposes have significantly improved neurosurgical practice and education for physicians and nurses.

Research Question: To what extent could comprehensive interventions (beyond treating patients) be effective in developing global neurosurgery from the outset in low and middle-income countries?

Material And Method: A retrospective review of a 14- year period (2008-2022) of NEDF activities highlighting landmarks, projects, and evolving collaborations in Zanzibar was carried out.

Supplemental ferulic acid does not affect metabolic markers and improves some oxidative damage parameters in diabetic rats.

This study investigated the differences in health outcomes associated with ferulic acid (FA) supplementation in animals before the induction of diabetes with streptozotocin (STZ) treatment and post-STZ treatment. 18 male Wistar rats were equally distributed into three groups: groups 1 and 2 received FA (50 mg/kg body weight) supplementation one week before STZ treatment (60 mg/kg body weight, intraperitoneal) and one week after STZ treatment, respectively; group 3 received STZ without FA supplementation. FA supplementation was continued for 12 weeks after STZ treatment.

Insights into the Differential Composition of Stem-Loop Structures of Nanoviruses and Their Impacts.

Multipartite viruses package their genomic segments independently and mainly infect plants; few of them target animals. is a family of multipartite single-stranded DNA (ssDNA) plant viruses that individually encapsidate ssDNAs of ~1 kb and transmit them through aphids without replication in aphid vectors, thereby causing important diseases in host plants, mainly leguminous crops. All of these components constitute an open reading frame to perform a specific role in nanovirus infection.

University students' awareness of e-waste and its disposal practices in Pakistan: a construction of the conceptual framework.

Pakistan is among the few countries generating and receiving enormous e-waste, which posits a threat to its future generations. A systematic literature review also suggests exploring e-waste awareness in Asia to understand awareness and behavior. Therefore, the present study explored university students' awareness of e-waste and the factors hindering the disposal of laptops, personal computers, and cellphones and suggested a conceptual framework.

Sustainable landfill sites selection using geospatial information and AHP-GDM approach: A case study of Abha-Khamis in Saudi Arabia.

Social, environmental, and technical factors must be combined to solve the complex problem of ever-growing municipal solid waste (MSW) and minimize its negative impact on the environment. Saudi Arabia has launched a US$13 billion tourism strategy to transform the Asir region into a year-round tourist destination and has pledged to welcome 10 million local and foreign visitors by 2030. The estimated share of Abha-Khamis will increase to 7.

Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies.

Dihydropyrazole (1-22) derivatives were synthesized from already synthesized chalcones. The structures of all of the synthesized compounds were confirmed by elemental analysis and various spectroscopic techniques. Furthermore, the synthesized compounds were screened against α amylase as well as investigated for antioxidant activities.

Photobiomodulation Therapy Restores Olfactory Function Impaired by Photothrombosis in Mouse Olfactory Bulb.

An ischemic stroke typically accompanies numerous disorders ranging from somatosensory dysfunction to cognitive impairments, inflicting patients with various neurologic symptoms. Among pathologic outcomes, post-stroke olfactory dysfunctions are frequently observed. Despite the well-known prevalence, therapy options for such compromised olfaction are limited, likely due to the complexity of olfactory bulb architecture, which encompasses both the peripheral and central nervous systems.

Forecasting real exchange rate (REER) using artificial intelligence and time series models.

Forecasting is an attractive topic in every field of study because no one knows the exact nature of the underlying phenomena, but it can be guessed using mathematical functions. As the world progresses towards technology and betterment, algorithms are updated to understand the nature of ongoing phenomena. Machine learning (ML) algorithms are an updated phenomenon used in every task aspect.

Flubendiamide induced genetic and cellular damages directly influence the life cycle of the oriental leaf worm, Spodoptera litura.

Indiscriminate uses of insecticide greatly damage the environment as well as non-target organisms. Thus, multiple levels of bioassays can help better management of our environment. Flubendiamide is a phthalic acid diamide insecticide that ceases the function of insect muscle leading to paralysis and death.

Automated Uterine Fibroids Detection in Ultrasound Images Using Deep Convolutional Neural Networks.

Fibroids of the uterus are a common benign tumor affecting women of childbearing age. Uterine fibroids (UF) can be effectively treated with earlier identification and diagnosis. Its automated diagnosis from medical images is an area where deep learning (DL)-based algorithms have demonstrated promising results.

An autoregressive distributed lag approach for estimating the nexus between CO2 emissions and economic determinants in Pakistan.

Carbon dioxide (CO2) emissions have become a critical aspect of the economic and sustainable development indicators of every country. In Pakistan, where there is a substantial increase in the population, industrialization, and demand for electricity production from different resources, the fear of an increase in CO2 emissions cannot be ignored. This study explores the link that betwixt CO2 emissions with different significant economic indicators in Pakistan from 1960 to 2018 using the autoregressive distributed lag (ARDL) modelling technique.

Graphene oxide reinforced biopolymeric (chitosan) hydrogels for controlled cephradine release.

In the current study, chitosan, poly (N-vinyl-2-pyrolidone) and polyamidoamine based hydrogels were prepared by Solution Casting Method using different quantity of graphene oxide (GO) for controlled cephradine (CPD) release. The hydrogels were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction, thermal analysis, scanning electron microscope and atomic force microscopy. FTIR results endorsed the presence of particular functionalities and developed interfaces in hydrogels.

Karachi Cancer Registry (KCR): Consolidated Data of 5-years 2017-2021.

Objective:  To collect and analyse epidemiologic data of all malignancies by age group and gender for the Karachi population to estimate the cancer incidence of 5-years (2017-2021) and identify major risk factors for setting priorities towards cancer control programs.

Study Design: Observational study. Place and Duration of the Study: Karachi Cancer Registry (KCR) Secretariat, Pakistan Health Research Council (PHRC), JPMC, Karachi, from 2017-2021.

Characterization and bioactivities of : In-silico modeling of as a potential drug source.

In current study the pharmaceutically active herbs was used against coccidiosis, caused by a protozoan: , lead to $ 3 billion loss annually. The aqueous and methanolic extracts of whole plants were applied to assess sporulation inhibition (spi) assay and calculated the inhibitory concentration (IC). For study 9 groups of 14 day old broiler chicks were infected with and three groups were treated different concentrations of methanolic extracts of and post infection.

Bupivacaine and morphine epidural use for refractory neuropathic pain relief in a Guillain-Barré syndrome patient.

Pain is common in the acute phase of Guillain-Barré Syndrome and can be severe and refractory. Pain in GBS may not always respond to contemporary pain therapy. An epidural can potentially be considered for the treatment of refractory pain after a careful patient-centered discussion with the patient about risks.

Ferricyanide photo-aquation pathway revealed by combined femtosecond Kβ main line and valence-to-core x-ray emission spectroscopy.

Reliably identifying short-lived chemical reaction intermediates is crucial to elucidate reaction mechanisms but becomes particularly challenging when multiple transient species occur simultaneously. Here, we report a femtosecond x-ray emission spectroscopy and scattering study of the aqueous ferricyanide photochemistry, utilizing the combined Fe Kβ main and valence-to-core emission lines. Following UV-excitation, we observe a ligand-to-metal charge transfer excited state that decays within 0.

Correlation Between Research Productivity During Medical School and Radiation Oncology Residency.

Purpose: This analysis investigates whether research productivity during medical school predicts future research productivity during radiation oncology residency.

Methods And Materials: At our institution, there have been 20 medical students who graduated between 2005 and 2015 and subsequently completed their residency training in radiation oncology. We built a database of all PubMed-indexed publications in which these former students were the first author or coauthor.

Looking at both sides, outcomes of positive workplace relational systems: A phenomenological study.

Relational systems are like a gear wheel in organizational processes that keeps employees connected and moving. These relationships are developed and maintained within the work environment for task accomplishment. But these relational systems are originating other outcomes that directly and indirectly affect the organizational process.

Noninvasive Continuous Glucose Monitoring With a Novel Wearable Dial Resonating Sensor: A Clinical Proof-of-Concept Study.

Background: A noninvasive, wearable continuous glucose monitor would be a major advancement in diabetes therapy. This trial investigated a novel noninvasive glucose monitor which analyzes spectral variations in radio frequency/microwave signals reflected from the wrist.

Methods: A single-arm, open-label, experimental study compared glucose values from a prototype investigational device with laboratory glucose measurements from venous blood samples (Super GL Glucose Analyzer, Dr.

Relationship between hedonic hunger and subjectively assessed sleep quality and perceived stress among university students: A cross-sectional study.

Purpose: This study examined the relationship between hedonic hunger (HH), sleep quality, and stress levels among university students in the United Arab Emirates and the Kingdom of Bahrain.

Methods: We used a cross-sectional design with participants (N = 565) recruited via convenience sampling. Data were collected with a self-administered, standardized, and validated online questionnaire.

Chondroblastoma of foot bones; a clinicopathological study of 29 cases confirming the diagnostic utility of H3K36M and H3G34W antibodies at an uncommon site.

Objective: Chondroblastoma (CB) is a benign cartilaginous bone neoplasm which commonly occurs in long bones of adolescents. CB can uncommonly involve foot. Its mimics include both benign and malignant lesions.