lncRNA Promotes Metastasis of Non-Small Cell Lung Cancer Through EZH2-Mediated Activation of Hippo/NOTCH1 Signaling Pathways.

Objective: Although growing evidences have showed that long non-coding RNA (lncRNAs) plasmacytoma variant translocation 1 () plays a critical role in the progression of non-small cell lung cancer (NSCLC), there are still many unsolved mysteries remains to be deeply elucidated. This study aimed to find a new underlying mechanism of in regulating the tumorigenesis and development of NSCLC.

Materials And Methods: In this experimental study, Quantitative reverse transcription polymerase chain reaction (qRTPCR) was used to profile the expression of in NSCLC tissues and cells.

Rational Design of Efficient Organometallic Ir(III) Complexes for High-Performance, Flexible, Monochromatic, and White Light-Emitting Electrochemical Cells.

Highly efficient light-emitting electrochemical cells (LECs) have attracted tremendous interest because of their simple structures and low-cost fabrication processing, showing great potential for full-color displays and solid-state lighting. In this work, we rationally designed and synthesized two red-emitting cationic Ir(III) complexes, [Ir(tBuPBI)(biq)]PF () and [Ir(tBuPBI)(qibi)]PF (), in which a tert-butyl-functionalized 1,2-diphenyl-1-benzo[]imidazole (PBI) unit and conjugated 2,2'-biquinoline (biq) and 2-(1-phenyl-1-benzo[]imidazol-2-yl)quinolone (qibi) were employed as cyclometalated and ancillary ligands, respectively. The introduced tert-butyl group led to homogeneous and highly emissive thin films by increasing the solubility and suppressing the strong intermolecular interactions due to steric hindrance.

MicroRNA-497-5p negatively regulates the proliferation and cisplatin resistance of non-small cell lung cancer cells by targeting YAP1 and TEAD1.

Background: MicroRNAs (miRNAs) are crucial regulators in the pathological processes and drug resistance of lung cancer. In this study, we investigated the role of miR-497-5p in modulating the function of non-small cell lung cancer (NSCLC).

Methods: MiR-497-5p expression in lung cancer tissues and cells was evaluated by qRT-PCR.

All-Solution-Processed Perovskite Quantum Dots Light-Emitting Diodes Based on the Solvent Engineering Strategy.

Perovskite quantum dots (PeQDs) have emerged as a new kind of nanomaterial in various applications, especially light-emitting diodes (LEDs). However, the synthesis of PeQDs is relatively complicated and the electron transport layer (ETL) is usually fabricated in a vacuum because of the dissolution of PeQDs films in organic solvents, which will increase the difficulty and cost in mass production. Here, a simple one-step "ultrasonic bath" treatment to synthesis PeQDs is adopted and applied into the PeQDs-LEDs.

Improving Charge Injection via a Blade-Coating Molybdenum Oxide Layer: Toward High-Performance Large-Area Quantum-Dot Light-Emitting Diodes.

A solution-processed molybdenum oxide (MoO ) as the hole injection layer (HIL) by doctor-blade coating was developed to improve the efficiency and lifetime of red-emitting quantum-dot light-emitting diodes (QD-LEDs). It has been demonstrated that by adding isopropyl alcohol into the MoO precursor during the doctor-blade coating process, the morphology, composition, and the surface electronic structure of the MoO HIL could be tailored. A high-quality MoO film with optimized charge injection was obtained, based on which all-solution-processed highly efficient red-emitting QD-LEDs were realized by using a low-cost doctor-blade coating technique under ambient conditions.

Large Size Color-tunable Electroluminescence from Cationic Iridium Complexes-based Light-emitting Electrochemical Cells.

Solution-processable light-emitting electrochemical cells (LECs) with simple device architecture have become an attractive candidate for application in next generation lighting and flat-panel displays. Herein, single layer LECs employing two cationic Ir(III) complexes showing highly efficient blue-green and yellow electroluminescence with peak current efficiency of 31.6 cd A(-1) and 40.

Autonomic nervous function and arrhythmias in patients with acute viral myocarditis during a 6-month follow-up period.

Objective: It was our aim to study the outcome of autonomic nervous function (ANF), heart rate variability (HRV) and arrhythmias in patients with acute viral myocarditis in a 6-month follow-up period after the diagnosis.

Methods: ANF was measured in patients with acute viral myocarditis 1, 3 and 6 months after the disease was diagnosed. HRV and arrhythmias were monitored by 24-hour electrocardiogram during the follow-up examination.

[Change in endothelial progenitor cells and endothelial function in patients with unstable angina pectoris].

Objective: To investigate the relationship between endothelial progenitors cells (EPCs) and endothelium-dependent vasodilation in patients with unstable angina pectoris.

Methods: Thirty patients with unstable angina pectoris (UAP) and thirty control subjects were recruited. Flow-mediated dilation (FMD) in the brachial artery was evaluated by using ultrasound Doppler flow method.

[Sevoflurane-N2O inhalation anaesthesia with laryngeal mask airway and propofol-ketamine intravenous anaesthesia in strabismus surgery].

Objective: To investigate the advantages and disadvantages of sevoflurane-N2O inhalation anesthesia with laryngeal mask airway (LMA) and propofolketamine total intravenous anaesthesia in children undertaking strabismus surgery.

Methods: Eighty children undertaking strabismus surgery were randomly divided into sevoflurane-N2O inhalation anaesthesia group with LMA (volatile group, n=40) and propofol-ketamine total intravenous anesthesia group (TIVA group, n=40). LMA was used to secure respiratory airway in the volatile group, but LMA or endotracheal intubation was not used in the TIVA group.

[Impaired endothelium-dependent vasodilation and arterial elasticity in patients with coronary artery disease].

Objective: To investigate the change in endothelium-dependent vasodilation and arterial elasticity and the association between them in patients with coronary artery disease (CAD).

Methods: Thirty patients with CAD and thirty control subjects were recruited for this study. Flow-mediated dilation (FMD) in the brachial artery was evaluated by ultrasound Doppler flow method.