Macrophages can determine the ultimate outcome of the foreign body reaction (FBR). Although researchers confirmed that differences in the elemental composition of the implant interface can lead to varying levels of biological function, the mechanism underlying the polarization directions of macrophages induced by varying oxygen proportions remains unclear. This research presented the fabrication of a deoxygenated hydroxyapatite (dHAP) surface to investigate the impact of oxygen content on macrophage activation.
View Article and Find Full Text PDFTwo luminescent lead phosphonates with two-dimensional (2D) layer and three-dimensional (3D) framework structure, namely, Pb[(L)(Hssc)(HO)] () and [Pb(L)(bts)(HO)]·HO () (HL = O(CHCH)NCHPOH, HL = HPOCHNH(CH)NHCHPOH, Hssc = 5-sulfosalicylic acid, NaHbts = 5-sulfoisophthalic acid sodium) have been prepared via hydrothermal techniques. The two compounds not only show excellent thermal stability but also remain intact in aqueous solution within an extensive pH range. Moreover, the atomic absorption spectroscopy analysis experiment indicates that there does not exist the leaching of Pb ions from the lead phosphonates, which show they are nontoxic in aqueous solution.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
October 2011
A new approach for characterization of agarose gel permeability under compression at different loading velocities is proposed. Uniaxial compression tests on thin agarose gel specimens in a rigid porous confinement cell immersed in a water bath are undertaken. The equilibrium response of the gel, which is assumed to be achieved under extremely low-loading velocity (of the order of tens nanometers per second) is considered to be the response of the hydrated gel scaffold.
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