Poly(A)-specific ribonuclease protein promotes the proliferation, invasion and migration of esophageal cancer cells.

Background: Bioinformatics analysis showed that the expression of the poly(A)-specific ribonuclease (PARN) gene in gastric cancer, head and neck squamous cell carcinoma, melanoma, cervical cancer and lung squamous cell carcinoma tissues was significantly higher than that in normal tissues and was associated with high stage and poor prognosis. The expression of the PARN gene in esophageal cancer (EC) tissue is also significantly higher than that in normal tissues, but the effect of PARN on the proliferation, migration and invasion of EC cells remains unclear.

Aim: To investigate the relationship between PARN and the proliferation, migration and invasion of EC cells.

[Effects of minimally invasive versus open esophagectomy on circulating tumor cells in patients with esophageal cancer].

Objective: To investigate the effects of minimally invasive esophagectomy (MIE) and open esophagectomy (OE) on the level of circulating tumor cells (CTCs) in patients with esophageal cancer (EC).

Methods: A total of 73 patients with EC undergoing MIE (n=38) or OE (n=35) in our department between October, 2015 and October, 2017 were enrolled, with 10 patients with benign esophagus disease and 10 healthy volunteers as controls. The levels of CTCs in the peripheral blood of the participants were detected using CanPatrol technique and analyzed for their association with the operation methods and perioperative complications.

ω-3 Polyunsaturated Fatty Acid Postconditioning Protects the Isolated Perfused Rat Heart from Ischemia-Reperfusion Injury.

Aims: This study aimed to evaluate the cardioprotective effects of ω-3 polyunsaturated fatty acids (PUFAs) postconditioning against ischemia-reperfusion (I/R) injury.

Methods: Sixty Sprague-Dawley rats were randomly divided into 4 groups (n = 15 for each) and used to generate the Langendorff isolated perfused rat heart model. The sham group received a continuous perfusion of 150 min.

[Relationship between early spontaneous cardioversion of atrial fibrillation and thyroid hormone metabolism after mitral replacement in patients with rheumatic heart disease].

Objective: To analyze the relationship between early spontaneous cardioversion of atrial fibrillation (AF) and thyroid hormone metabolism after mitral replacement in patients with rheumatic heart disease, and explore the treatment strategy of early spontaneous cardioversion after mitral valve replacement.

Methods: According to the occurrence of cardioversion, 138 patients with mitral valve replacement were divided into conversion group and non-conversion group, and based on the duration of sinus rhythm, the patients in conversion group were divided into < 3 days group and > 3 days group. Triiodothyronine (T3) was detected by radioimmunoassay in all the patients.

[Hemocompatibility evaluation in vitro of small-caliber expanded polytetrafluoroethylene vessel with silk fibroin coating sulfonated by low temperature plasma].

Objective: To evaluate the hemocompatibility of a small-caliber expanded polytetrafluoroethylene vessel with silk fibroin coating sulfonated by low temperature plasma treatment.

Methods: The composite blood vessel was prepared by first coating the small-caliber expanded polytetrafluoroethylene vessel with silk fibroin followed by sulfonation by low temperature plasma treatment. After hemolysis test in vitro, dynamic coagulation time test, blood platelet adhesion test, and recalcification time test were performed to evaluate the hemocompatibility of the composite blood vessel.

[Expression of special AT-rich sequence-binding protein mRNA and its clinicopathological significance in non-small cell lung cancer].

Objective: To detect the expression of AT-rich sequence-binding protein (SATB1) mRNA in non-small cell lung cancer (NSCLC) and explore the role of SATB1 in the development of NSCLC.

Methods: The total RNA was extracted from NSCLC tissues and normal lung tissues and reverse transcribed into cDNA. Real-time fluorescence quantitative RT-PCR was performed for detecting the expression of SATB1 mRNA these tissues.

Application of jejunum with vascular pedicle in reconstruction of the digestive tract.

Objective: To reconstruct the digestive tract using the jejunum with vascular pedicle after esophagectomy or gastrectomy, and observe the therapeutic effects and the patients' quality of life after the operation.

Methods: This study included a total of 25 patients, 10 of whom received proximal subtotal gastrectomy followed by reconstruction of the digestive tract with P-shaped jejunum for anastomosis of the esophagus and the residual stomach, 15 had total gastrectomy and anastomosis of the P-shaped jejunum with the esophagus inferior to the arch of aorta, with another 2 having total gastrectomy and the anastomosis superior to the arch of aorta. The pH value of the esophagus was tested, barium meal and gastroscopy were carried out 3 months after the operations, and the patients' quality of life assessed.

[Experience with coronary artery bypass grafting and concomitant procedures in 21 cases].

Objective: To review our experience with coronary artery bypass grafting (CABG) and its concomitant procedures.

Methods: From December, 1998 to December, 2002, 21 patients underwent CABG and their clinical data were analyzed.

Results: Nineteen patients were discharged uneventfully after the procedure.

[Minimally invasive closure of atrial septal defect without extracorporeal circulation: report of 5 cases].

Objective: To review our experience with a new surgical approach for closure of atrial septal defect (ASD) through a minimally invasive method without extracorporeal circulation.

Methods: Five female patients (age range, 7-38 years) with secondary atrial septal defect ranging from 1.8 to 3.