Lathyrane diterpenoids from and their antitumor activities in human osteosarcoma cells.

Two new lathyrane-type diterpenoids, jatropodagins A and B ( and ), and five known analogues (-), were isolated from the stems of . Their structures and absolute configurations were elucidated by spectroscopic data and calculated ECD analyses. The cytotoxicities of all the lathyrane-type diterpenoids (-) were evaluated against two human osteosarcoma cell lines (Saos-2 and MG-63).