Publications by authors named "Qun Y Zhou"

Micro-Doppler effect is a vital feature of a target that reflects its oscillatory motions apart from bulk motion and provides an important evidence for target recognition with radars. However, establishing the micro-Doppler database poses a great challenge, since plenty of experiments are required to get the micro-Doppler signatures of different targets for the purpose of analyses and interpretations with radars, which are dramatically limited by high cost and time-consuming. Aiming to overcome these limits, a low-cost and powerful simulation platform of the micro-Doppler effects is proposed based on time-domain digital coding metasurface (TDCM).

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Manipulations of multiple carrier frequencies are especially important in a variety of fields like radar detection and wireless communications. In conventional radio-frequency architecture, the multi-frequency control is implemented by microwave circuits, which are hard to integrate with antenna apertures, thus bringing the problems of expensive system and high power consumption. Previous studies demonstrate the possibility to jointly control the multiple harmonics using space-time-coding digital metasurface, but suffer from the drawback of inherent harmonic entanglement.

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A space-time coding metasurface (STCM) operating in the sub-terahertz band to construct new-architecture wireless communication systems is proposed. Specifically, a programmable STCM is designed with varactor-diode-tuned metasurface elements, enabling precise regulation of harmonic amplitudes and phases by adjusting the time delay and duty cycle of square-wave modulation signal loaded on the varactor diodes. Independent electromagnetic (EM) regulations in the space and time domains are achieved by STCM to realize flexible beam manipulations and information modulations.

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The rapid development of space-time-coding metasurfaces (STCMs) offers a new avenue to manipulate spatial electromagnetic beams, waveforms, and frequency spectra simultaneously with high efficiency. To date, most studies are primarily focused on harmonic generations and independent controls of finite-order harmonics and their spatial waves, but the manipulations of continuously temporal waveforms that include much rich frequency spectral components are still limited in both theory and experiment based on STCM. Here, we propose a theoretical framework and method to generate frequency-modulated continuous waves (FMCWs) and control their spatial propagation behaviors simultaneously via a novel STCM with nonlinearly periodic phases.

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Article Synopsis
  • Choriocarcinoma (CC) is a serious form of gestational trophoblastic disease that often arises from complete hydatidiform moles, but the mechanisms behind its development and progression remain unclear.* -
  • Recent research has identified endocrine gland-derived vascular endothelial growth factor (EG-VEGF) as a crucial factor in trophoblast growth, which can be targeted for CC treatment through various experimental approaches, including clinical investigations and a new mouse model.* -
  • Findings indicate that elevated levels of EG-VEGF are associated with CC, and using antagonists to block its receptors can significantly reduce tumor progression and support pregnancy, offering a potential alternative to traditional chemotherapy.*
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Proteins that bind to G protein-coupled receptors have been identified as regulators of receptor localization and signaling. In our previous studies, a cytoskeletal protein, actin-binding protein 280 (ABP-280), was found to associate with the third cytoplasmic loop of dopamine D(2) receptors. In this study, we demonstrate that ABP-280 also interacts with dopamine D(3) receptors, but not with D(4) receptors.

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