Depression and anxiety of medical students at Kunming Medical University during COVID-19: A cross-sectional survey.

An isolation strategy was used to control the transmission and rapid spread of COVID-19 in Yunnan. As a result, students were supposed to stay at home and disrupted their outside activities. It led to a detrimental influence on students' mental health.

[Roles of G protein-coupled receptor 30 in the effects of genistein on apoptosis and cell cycle in human thyroid squamous cells SW579].

Objective: Investigate the estrogen receptor expression in human thyroid squamous cell carcinoma SW579 and the effects of genistein on the apoptosis and cycle of SW579 and its mechnism.

Methods: The real-time PCR was applied to detect the expression of estrogen receptor(ER)α、ERβ and G protein-coupled receptor(GPR)30 in human thyroid squamous cell line SW579; MTT was used to test the effect of genistein on cell proliferation in the SW579 cells before and after blocking GPR30; flow cytometry was explorited to measure the effect of genistein on the cell cycle and apoptosis in the SW579 was detected before and after blocking GPR30.

Results: The high concentration of genistein promoted the expression of ERβ and GPR30 in the SW579 cells, but ERα was not expressed.

Prophylactic Effects of on Anxiety and Depression-Like Phenotypes After Chronic Stress: A Role of the Gut Microbiota-Inflammation Axis.

Stress disturbs the balance of the gut microbiota and stimulates inflammation-to-brain mechanisms. Moreover, stress leads to anxiety and depressive disorders. displays distinct anti-inflammatory effects.

Using Mind Maps to Improve Medical Student Performance in a Pharmacology Course at Kunming Medical University.

Objective: To determine whether students using mind maps would improve their performance in a final examination at the end of lecture-based pharmacology course.

Study Design: Aquasi-experimental study.

Place And Duration Of Study: Kunming Medical University, from September 2014 to January 2015.

[The change of cancer-related genes expression profile in Nthy-ori-3-1 cell induced by the pesticide amitrole].

Objective: To explore the possible mechanism of amitrole causing thyroid tumor in Nthy-ori-3-1 cell by differential expression microarray analysis.

Methods: After the Nthy-ori-3-1cells were treated with 1 ~ 100 g / m L amitrole for 24 h, and the effect of amitrole on the proliferation of the cells was detected by MTT assay. Then cells were treated with 100 g / m L amitrole for 24 h, and the differential expression microarray was tested.

Maturation and emigration of single-positive thymocytes.

T lymphopoiesis in the thymus was thought to be completed once it reaches the single positive (SP) stage, a stage when T cells are "fully mature" and waiting to be exported at random or follow a "first-in-first-out" manner. Recent evidence, however, has revealed that the newly generated SP thymocytes undergo a multistage maturation program in the thymic medulla. Such maturation is followed by a tightly regulated emigration process and a further postthymic maturation of recent thymic emigrants (RTEs).