Risk factors for the development of hyperuricemia: A STROBE-compliant cross-sectional and longitudinal study.

Hyperuricemia has received increasing attention as a major public health problem. This study aims to investigate the risk factors for hyperuricemia and to explore the relationship between changes in biochemical variables and incident hyperuricemia.A cross-sectional and subsequently prospective study was performed among adults who took their health checkups at Zhejiang University Hospital.

PLA2G4A mutants modified protective effect of tea consumption against colorectal cancer.

Purpose: The primary aim was to respectively evaluate PLA2G4A mutants modifying protective effect of tea consumption against colorectal cancer (CRC), colon and rectal cancer.

Methods: All participants were recruited from January 2006 to April 2008. The information about tea consumption was collected by a structured questionnaire.

Inhibitory effect of hypoxia inducible factor-1 antisense oligonucleotide on growth of human hepatocellular carcinoma cells.

Object: To observe the inhibitory effect of Hypoxia inducible factor-1 antisense oligonuclecotide on growth of human hepatocellular carcinoma cells and gene expression of HIF-1, in order to seek a new gene therapy for hepatocellular carcinoma.

Methods: Six Hypoxia inducible factor-1 antisense oligonuclecotides with various concentrations (0.2 micromol/l, 0.

Transient elevation of hepatic enzymes in volunteers after intake of alcohol.

Background: In the organs that mediate alcohol effects on the human body and its health, the liver plays a particular important role. This study was designed to detect the changes of hepatic enzymes after alcohol intake and evaluate the corresponding damage to the human body.

Methods: Fifteen volunteers were included according to the criteria.