Encapsulation of thyme essential oil in dendritic mesoporous silica nanoparticles: Enhanced antimycotic properties and ROS-mediated inhibition mechanism.

Dendritic mesoporous silica nanoparticles (DMSNs) have emerged as promising nanocarriers due to their unique three-dimensional structure and tunable pore characteristics. This study investigates the potential of DMSNs to deliver thyme essential oil (TEO) for enhanced antifungal activity against Fusarium oxysporum (F. oxysporum), a major plant pathogen.

Sphingobium sp. SJ10-10 encodes a not-yet-reported chromate reductase and the classical Rieske dioxygenases to simultaneously degrade PAH and reduce chromate.

Both polycyclic aromatic hydrocarbons (PAHs) and heavy metals persist in the environment and are toxic to organisms. Their co-occurrence makes any of them difficult to remove during bioremediation and poses challenges to environmental management and public health. Microorganisms capable of effectively degrading PAHs and detoxifying heavy metals concurrently are required to improve the bioremediation process.

Ultra-low-dose spectral-detector computed tomography for the accurate quantification of pulmonary nodules: an anthropomorphic chest phantom study.

Purpose: To assess the quantification accuracy of pulmonary nodules using virtual monoenergetic images (VMIs) derived from spectral-detector computed tomography (CT) under an ultra-low-dose scan protocol.

Methods: A chest phantom consisting of 12 pulmonary nodules was scanned using spectral-detector CT at 100 kVp/10 mAs, 100 kVp/20 mAs, 120 kVp/10 mAs, and 120 kVp/30 mAs. Each scanning protocol was repeated three times.

Flagellar brake protein YcgR interacts with motor proteins MotA and FliG to regulate the flagellar rotation speed and direction.

In and related species, flagellar brake protein YcgR responds to the elevated intracellular c-di-GMP, decreases the flagellar rotation speed, causes a CCW rotation bias, and regulates bacterial swimming. Boehm et al. suggested that c-di-GMP-activated YcgR directly interacted with the motor protein MotA to curb flagellar motor output.

A Fabry-Perot Sensor with Cascaded Polymer Films Based on Vernier Effect for Simultaneous Measurement of Relative Humidity and Temperature.

In this paper, fiber sensor based on Vernier effect for simultaneous measurement of relative humidity (RH) and temperature is proposed. The sensor is fabricated by coating two kinds of ultraviolet (UV) glue with different refractive indexes (RI) and thicknesses on the end face of a fiber patch cord. The thicknesses of two films are controlled to generate the Vernier effect.

Wogonin Restrains the Malignant Progression of Lung Cancer Through Modulating MMP1 and PI3K/AKT Signaling Pathway.

Background: Wogonin, a natural flavonoid compound, represses cancer cell growth and induces cancer cell apoptosis in diverse malignancies. However, the function of Wogonin in lung cancer cells and its regulatory mechanism deserve to be identified.

Methods: A549 and H460 cells were treated with Wogonin, and the cell growth, apoptosis, migration and invasion were measured by CCK-8 and EdU, flow cytometry and Transwell assays.

Long noncoding RNA regulatory factor X3- antisense RNA 1 promotes non-small cell lung cancer via the microRNA-577/signal transducer and activator of transcription 3 axis.

Lung cancer is the most frequent malignancy, and non-small cell lung cancer (NSCLC) is its most common pathological type. Molecular targeted therapy has been testified to be effective in intervening in the occurrence and development of malignancies. This study investigates the effect of lncRNA Regulatory Factor X3- antisense RNA 1 (RFX3-AS1) in NSCLC progression.

Evaluating the impact of personalized rehabilitation nursing intervention on postoperative recovery of respiratory function among thoracic surgery intensive care unit patients: A protocol for systematic review and meta-analysis.

Background: Exercise tolerance and lung function can be improved by pulmonary rehabilitation. As a result, it may lower thoracic surgery intensive care unit (ICU) patients' postoperative problems and death. Enhanced recovery after surgery has advanced significantly in the perioperative care of thoracic surgery ICU patients in recent years, and it now plays an essential role in improving ICU patients' postoperative prognosis.

Prevalence of Sialorrhea Among Amyotrophic Lateral Sclerosis Patients: A Systematic Review and Meta-Analysis.

Background And Objectives: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative motor neuron disease (MND), and sialorrhea is a known symptom in patients with ALS, which may cause a social embarrassment and discomfort. However, people do not pay attention to sialorrhea up to now. This study is aimed at conducting a systematic review and meta-analysis of the pooled prevalence of sialorrhea in ALS patients all around the world and raising awareness of salivation.

[Advances in bacterial Rieske non-heme iron ring-hydroxylating dioxygenases that initiate polycyclic aromatic hydrocarbons degradation].

Polycyclic aromatic hydrocarbons (PAHs) are a class of persistent organic pollutants, which have received widespread attentions due to their carcinogenic and mutagenic toxicity. The microbial degradation of PAHs are usually started from the hydroxylation, followed by dehydrogenation, ring cleavage and step-by-step removal of branched chains, and finally mineralized by the tricarboxylic acid cycle. Rieske type non-heme iron aromatic ring-hydroxylating dioxygenases (RHOs) or cytochrome P450 oxidases are responsible for the conversion of hydrophobic PAHs into hydrophilic derivatives by the ring hydroxylation.

Polarization-sensitive and active controllable electromagnetically induced transparency in U-shaped terahertz metamaterials.

Electromagnetically induced transparency (EIT) phenomenon is observed in simple metamaterial which consists of concentric double U-shaped resonators (USRs). The numerical and theoretical analysis reveals that EIT arises from the bright-bright mode coupling. The transmission spectra at different polarization angle of incident light shows that EIT transparency window is polarization sensitive.

Nek9,a sensitive immunohistochemical marker for Schwannian, melanocytic and myogenic tumours.

Aims: In our previous study, striking Nek9 staining was observed in peripheral nerves for the first time. Therefore, in the current study, we aimed to detect Nek9 expression in peripheral nerve sheath tumours, melanocytic tumours and their mimics.

Methods: The expression of Nek9 was analysed in 234 mesenchymal tumours including schwannoma, neurofibroma, malignant peripheral nerve sheath tumour (MPNST), melanoma and their mimics adopting immunohistochemistry.

[Real-time cell analysis combined with pattern recognition to evaluate anaphylaxis of Zushima Injection].

This paper was aimed to establish a new method for evaluating the anaphylactoid reaction of 15 batches of Zushima Injection from different manufacturers in vitro. Basophilic leukemia cell line RBL-2 H3 cells were cultured in vitro and Compound 48/80 was selected as positive drug. Real-time cell analysis(RTCA) system was used to detect the changes of cell index(CI) value after drug intervention.

Temperature compensation of optical alternating magnetic field sensor via a novel method for on-line measuring.

The variation of environment temperature is a crucial problem for optical magnetic field sensors based on the magneto-optical crystal. In this paper, we propose a novel temperature compensation method for optical alternating magnetic field measuring by analyzing the demodulation principle and establishing the temperature compensation model, which can implement the functions of temperature compensation and on-line measuring simultaneously. Both the temperature and the alternating magnetic field flux density can be obtained only by adding two magnet rings on the magnetic field sensor.

Multiple Fano resonances with flexible tunablity based on symmetry-breaking resonators.

A symmetry-breaking nanostructure is proposed to achieve multiple Fano resonances. The nanostructure consists of an asymmetric ring resonator coupled to a plasmonic waveguide. The broken symmetry is introduced by deviating the centers of regular ring.

Cyclin-dependent kinase subunit 2 overexpression promotes tumor progression and predicts poor prognosis in uterine leiomyosarcoma.

Cyclin-dependent kinase subunit (CKS) 2 is a member of the CKS family, which plays an important role in the regulation of meiosis and mitosis. Overexpression of CKS2 has been reported in several types of tumors. However, few studies have investigated its role in uterine leiomyosarcoma (ULMS).

Optimal design of high-power cascade co-pumping Er/Yb-codoped fiber lasers.

The Yb-ASE problem has been a main obstacle to the power scaling of Er/Yb-codoped fiber lasers (EYDFLs). In this Letter, cascade co-pumping high-power EYDFLs, i.e.

Magnetic-field sensor with self-reference characteristic based on a magnetic fluid and independent plasmonic dual resonances.

A magnetic-field sensor with self-reference characteristic based on metal-dielectric-metal (MDM) plasmonic waveguides and a magnetic fluid (MF) is proposed and theoretically investigated. Independent dual resonances are supported by the coupled resonator-waveguide system. The physical mechanisms of dual resonances are analyzed by the temporal coupled-mode theory.

Contrast optimization in broadband passive polarimetric imaging based on color camera.

Broadband polarimetric imaging consists of forming an image under spectrally wide illumination after having optimized the polarization state analyzer (PSA) to maximize the target/background discriminability. In previous works, the image sensor was monochrome, and only the intensity contrast was optimized. However, due to its spectrally varying response, the PSA not only changes the light's intensity, but also its color.

Initial exploration of coronary stent image subtraction using dual-layer spectral CT.

Objectives: This study aimed to investigate the feasibility of coronary stent image subtraction using spectral tools derived from dual-layer spectral computed tomography (CT).

Methods: Forty-three patients (65 stents) who underwent coronary CT angiography using dual-layer spectral CT were included. Conventional, 50-keV (kilo electron-volt), 100-keV, and virtual non-contrast (VNC) images were reconstructed from the same cardiac phase.

Optimal ellipsometric parameter measurement strategies based on four intensity measurements in presence of additive Gaussian and Poisson noise.

The two ellipsometric parameters of an isotropic sample can be measured with simplified polarimetry setups that acquire at least four intensity measurements. However, these measurements are perturbed by noise and the measurement strategy has to be optimized, in order to limit noise propagation. We determine two different measurement strategies that are optimal for both white Gaussian additive noise and Poisson shot noise.

Method for estimating the Stark splitting of rare-earth ions from the measured cross-section spectra.

A method to estimate the Stark levels of the rare-earth ions doped in a laser medium from the measured emission and absorption cross-sections is proposed. The method is based on the McCumber theory, which can calculate the emission/absorption cross-sections from the given Stark levels. By fitting the calculated emission/absorption spectra to the measured ones through a numerical optimization process, the Stark levels of the RE ions can be determined.

Numerical investigation of the thermal effect on Yb-cavity-copumped Er/Yb codoped fiber amplifiers.

Thermal effects are critical constraints for developing high-power Er/Yb-codoped fiber amplifiers (EYDFAs), especially those with an auxiliary Yb-band cavity. In this paper, we developed a numerical model to investigate the temperature-dependent effects on EYDFAs with an Yb-band cavity with consideration of thermal-induced cross-section changes. Our results show that the quantum-defect-induced heat affects the performance of the EYDFA, and its effect varies with the resonant wavelength of the Yb-band cavity.

Sensor based on macrobent fiber Bragg grating structure for simultaneous measurement of refractive index and temperature.

A novel and compact all-fiber sensor based on a macrobent fiber Bragg grating (FBG) structure for simultaneous measurement of refractive index (RI) and temperature is proposed and experimentally investigated. The sensor can be easily fabricated by properly bending an FBG. The bending causes interference between the core mode and the whispering gallery mode, which induces another kind of dip in the transmission spectra of the sensor besides the sharp one of the FBG.

Highly efficient Er/Yb-codoped fiber amplifier with an Yb-band fiber Bragg grating.

In this Letter, a high-power Er/Yb-codoped fiber amplifier (EYDFA) with a high-reflection Yb-band fiber Bragg grating (FBG) at the pump end is experimentally investigated. The FBG was inscribed on a piece of double-clad fiber with a center wavelength of 1032 nm. Due to the selective reflection of the backward Yb-band amplified spontaneous emission (Yb ASE) by the FBG, a co-pump-propagating Yb-band auxiliary signal was generated.