Publications by authors named "Quinn Silverglate"
Article Synopsis
- The study aimed to compare how well low-field 0.55 Tesla MRI detects and characterizes ground-glass opacities and fibrosis-like changes in the lungs of post-Covid patients compared to chest CT images.
- A total of 64 post-Covid individuals underwent 106 non-contrast MRI exams, with some participants also receiving CT imaging within a month of their MRI for comparison.
- The results showed higher consistency among CT readings for lung opacities and features compared to MRI, indicating that MRI may be less reliable than CT for evaluating lung issues in these patients.
Aortic mural thrombus in the absence of underlying aortic disease is rare and results in a risk of distant arterial embolization that can result in limb loss or other end organ damage. Current management involves open surgery, anticoagulation, and systemic thrombolysis; however, each carries inherent risks. We report the case of aortic thrombus with distal emboli in two patients, a 56-year-old man and a 68-year-old man, neither with underlying aortic pathology and both presenting with limb threatening ischemia.
View Article and Find Full Text PDFMyotonic dystrophy type 1 (DM1) is an autosomal dominant, CTG•CAG microsatellite expansion disease. Expanded CUG repeat RNA sequester the muscleblind-like (MBNL) family of RNA-binding proteins, thereby disrupting their normal cellular function which leads to global mis-regulation of RNA processing. Previously, the small molecule furamidine was shown to reduce CUG foci and rescue mis-splicing in a DM1 HeLa cell model and to rescue mis-splicing in the HSA DM1 mouse model, but furamidine's mechanism of action was not explored.
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