In this work, the experimental evidence of glass-like phonon dynamics and thermal conductivity in a nanocomposite made of GeTe and amorphous carbon is reported, which is of interest for microelectronics, and specifically phase change memories. It is shown that, the total thermal conductivity is reduced by a factor of three at room temperature with respect to pure GeTe, due to the reduction of both electronic and phononic contributions. This latter, similarly to glasses, is small and weakly increasing with temperature between 100 and 300 K, indicating a mostly diffusive thermal transport and reaching a value of 0.
View Article and Find Full Text PDFNeurospora crassa is a central organism in the history of twentieth-century genetics, biochemistry and molecular biology. Here, we report a high-quality draft sequence of the N. crassa genome.
View Article and Find Full Text PDFMutations in alpha-synuclein (alpha-Syn) cause Parkinson's disease (PD) in a small number of pedigrees with familial PD. Moreover, alpha-Syn accumulates as a major component of Lewy bodies and Lewy neurites, intraneuronal inclusions that are neuropathological hallmarks of PD. To better understand the pathogenic relationship between alterations in the biology of alpha-Syn and PD-associated neurodegeneration, we generated multiple lines of transgenic mice expressing high levels of either wild-type or familial PD-linked Ala-30 --> Pro (A30P) or Ala-53 --> Thr (A53T) human alpha-Syns.
View Article and Find Full Text PDFJ Helminthol
September 2001
The status of Schistosoma sinensium (samples from Thailand and from Sichuan, China) relative to other species of the genus Schistosoma was investigated using DNA sequences from the mitochondrial cytochrome c oxidase subunit 1 (CO1) gene (partial) and the nuclear ribosomal DNA second internal transcribed spacer 2 (ITS2). Trees inferred from these sequences place S. sinensium as sister to the S.
View Article and Find Full Text PDFAm J Respir Crit Care Med
September 2001
Elevated levels of ambient particulate matter (PM(10)) have been associated with increased cardiopulmonary morbidity and mortality. We previously showed that the deposition of particles in the lung induces a systemic inflammatory response that includes stimulation of the bone marrow. This marrow response is related to mediators released by alveolar macrophages (AM) and in this study we measured cytokines produced by human AM exposed to ambient particles of different composition and size.
View Article and Find Full Text PDFZhonghua Xue Ye Xue Za Zhi
October 1998
Objective: To report the result of gene identification and pedigree analysis of the double mutation heterozygote of beta-thalassemia[-28(A-->G).CD17(A-->T)/N].
Methods: Polymerase chain reaction in combination with dot-blot hybridization of allele-specific oligonucleotide(PCR/ASO) probes was used.
Zhonghua Zhong Liu Za Zhi
May 1997
Objective: To evaluate the molecular biological mechanism of human hepatocellular carcinoma--DNA methylation pattern of certain oncogenes.
Methods: Methylation patterns of c-myc, c-N-ras oncogenes in human hepatocellular carcinoma were studied by the Southern blot technique and HpaII/MspI restriction endonucleases. The pathological changes were also analyzed.
The crystal structure of methyl beta-cellotrioside (methyl O-beta-D-glucopyranosyl-(1-->4)-O-beta-d_guycopyranosyl-(1-->4)-be ta-D- glucopyranoside) complexed with water and ethanol, C19H34O16. H2O.0.
View Article and Find Full Text PDFBlood PRL was measured with RIA in 22 males and 19 females with various degrees of renal insufficiency. At the same time, blood LH, FSH, testosterone were studied in all the male patients and 20 sex-age matched healthy subjects. The results showed that the levels of PRL and LH were increased, and the level of testosterone was decreased significantly in male uremic patients.
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