Publications by authors named "Quezia Estefani Silva Guimaraes"
World J Clin Oncol
February 2021
Article Synopsis
- - Chronic myeloid leukemia (CML) is characterized by the Philadelphia chromosome, marking it as the first cancer linked to a specific genetic anomaly, which is crucial for its diagnosis and treatment.
- - The development of targeted tyrosine kinase inhibitors (TKIs) has significantly improved survival rates for CML patients, despite potential side effects and issues with treatment discontinuation.
- - Newer TKIs and immunotherapy are being explored as alternatives due to resistance problems with initial treatments, aiming to provide deeper molecular remission and possible cures for patients with CML.
