Biofilm Formation by in the Specific Context of Cystic Fibrosis.

is a major human pathogen whose characteristics support its success in various clinical settings including Cystic Fibrosis (CF). In CF, is indeed the most commonly identified opportunistic pathogen in children and the overall population. colonization/infection, either by methicillin-susceptible or methicillin-resistant strains, will become chronic in about one third of CF patients.

and : Emerging Pathogens Well-Armed for Life in the Cystic Fibrosis Patients' Lung.

In patients with cystic fibrosis (CF), the lung is a remarkable ecological niche in which the microbiome is subjected to important selective pressures. An inexorable colonization by bacteria of both endogenous and environmental origin is observed in most patients, leading to a vicious cycle of infection-inflammation. In this context, long-term colonization together with competitive interactions among bacteria can lead to over-inflammation.

High Occurrence of Bacterial Competition Among Clinically Documented Opportunistic Pathogens Including in Cystic Fibrosis.

Cystic Fibrosis (CF) airways favor abnormal microbial development. Infections are considered as polymicrobial and competition can be observed between microorganisms. The current literature on bacterial competition in CF mostly consists of studies with limited numbers of strains, mainly focused on the major pathogens () and () and does not give a comprehensive overview of the overall importance of bacterial interactions or the behavior of less often encountered emerging bacteria such as .