Publications by authors named "Quentin Hong"
Collapse of the protein homeostasis (proteostasis) can lead to accumulation and aggregation of unfolded proteins, which has been found to associate with a number of disease conditions including neurodegenerative diseases, diabetes and inflammation. Here we report a maleimide-functionalized tetraphenylethene (TPE)-derivatized fluorescent dye, TPE-NMI, which shows fluorescence turn-on property upon reacting with unfolded proteins in vitro and in live cells under proteostatic stress conditions. The level of unfolded proteins can be measured by flow cytometry and visualized with confocal microscopy.
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- The group's research over the past six years focuses on organic photovoltaics, exploring the development and application of organic materials.
- The team highlights the importance of understanding how synthetic methods and molecular properties impact the bulk material's characteristics and overall device performance.
- Insights gained from this work aim to enhance the effectiveness and scalability of organic solar cell technologies.