Publications by authors named "Quentin A Nickerson"
Unlabelled: The microbiome has increasingly been linked to cancer. Little is known about the lung and oral cavity microbiomes in smokers, and even less for electronic cigarette (EC) users, compared with never-smokers. In a cross-sectional study (n = 28) of smokers, EC users, and never-smokers, bronchoalveolar lavage and saliva samples underwent metatranscriptome profiling to examine associations with lung and oral microbiomes.
View Article and Find Full Text PDFBiomarkers of Exposure and Effect in the Lungs of Smokers, Nonsmokers, and Electronic Cigarette Users.
Cancer Epidemiol Biomarkers Prev
February 2020
Article Synopsis
- Nicotine-containing e-cigarette use is increasing, but there are significant knowledge gaps regarding their long-term effects and the recent acute lung toxicity linked to vaping.* -
- A study of 73 individuals showed that e-cig users have lung inflammation levels that are closer to never-smokers than to traditional cigarette smokers, suggesting e-cigs are less harmful than cigarettes.* -
- Further research is needed to explore the unique effects of e-cigs, including studies on switching from smoking to e-cig use and the long-term health outcomes for former smokers.*
Electronic cigarette (e-cig) use is continuing to increase, particularly among youth never-smokers, and is used by some smokers to quit. The acute and chronic toxicity of e-cig use is unclear generally in the context of increasing reports of inflammatory-type pneumonia in some e-cig users. To assess lung effects of e-cigs without nicotine or flavors, we conducted a pilot study with serial bronchoscopies over 4 weeks in 30 never-smokers, randomized either to a 4-week intervention with the use of e-cigs containing only 50% propylene glycol (PG) and 50% vegetable glycerine or to a no-use control group.
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