Publications by authors named "Quanxing Zhao"
Objective: Organoids have recently been used as models to screen chemotherapy drugs in combination with hyperthermia treatment in colorectal cancer. Our research aimed to establish a library of patient-derived colorectal cancer organoids to evaluate synergism between chemotherapy drugs and hyperthermia; validate an index of the hyperthermia chemotherapy sensitization enhancement ratio (HCSER) to identify the chemotherapeutics most enhanced by hyperthermia; and recommend chemotherapy drugs for hyperthermic intraperitoneal treatment.
Methods: Organoids were grown from cells extracted from colorectal cancer patient samples or colorectal cancer cell lines.