Publications by authors named "Quanwen Li"

The A-site organic components of organic-inorganic hybrid metal halides (OIHMHs) significantly impact their crystal structure and optoelectronic properties. However, chemical modification of A-site cations has been mostly limited to commercial organic precursors, which restricts the structural variability of OIHMHs for optimal functionalities. Herein we have proposed an extendable synthesis approach to the direct procurability of various organic cations with desireable structures for the in situ construction of a library of OIHMH materials.

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Metal-organic frameworks (MOFs) have great prospects as adsorbents for industrial gas purification, but often suffer from issues of water stability and competitive water adsorption. Herein, we present a hydrolytically stable MOF that could selectively capture and recover trace SO from flue gas, and exhibits remarkable recyclability in the breakthrough experiments under wet flue-gas conditions, due to its excellent resistance to the corrosion of SO and the water-derived capillary forces. More strikingly, its SO capture efficiency is barely influenced by the increasing humidity, even if the pore filling with water is reached.

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α-Cobalt(II) (Co) hydroxide (compound ) incorporating cyanuric acid layers was synthesized via the solvothermal method. exhibited two distinct characteristics, which were different from reported α-Co hydroxides. (i) The presence of abundant consecutive hydrogen bonds between the adjacent hydroxide layers enhanced the driving force of crystallization along the direction of the axis.

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Dynamic twisting crystals, combining the features of dynamic crystals and twisting crystals, promise advanced applications in targeted drug delivery, biosensors, microrobots, and spiral optoelectronics. However, the determination of dynamic twisting crystals with specific directions remains a formidable challenge in practical applications. Herein, based on organic-inorganic hybrid metal halide (OIHMH) single crystals, we have realized the chirality-induced macroscopic twisting of single crystals driven by a thermo-induced topochemical dehydration reaction.

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Organic piezochromic materials that manifest pressure-stimuli-responses are important in various fields such as data storage and anticounterfeiting. The manipulation of piezofluorochromic behaviors for these materials is promising but remains a great challenge. Herein, a non-luminous components regulated strategy is developed and organic molecular cages (OMCs), a burgeoning class of crystalline organic materials with structural dynamics, are first explored for the design of piezofluorochromic materials with tunable luminescence.

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Aloe-emodin (AE) has been shown to inhibit the proliferation of several cancer cell lines, including human nasopharyngeal carcinoma (NPC) cell lines. In this study, we confirmed that AE inhibited malignant biological behaviors, including cell viability, abnormal proliferation, apoptosis, and migration of NPC cells. Western blotting analysis revealed that AE upregulated the expression of DUSP1, an endogenous inhibitor of multiple cancer-associated signaling pathways, resulting in blockage of the extracellular signal-regulated kinase (ERK)-1/2, protein kinase B (AKT), and p38-mitogen activated protein kinase(p38-MAPK) signaling pathways in NPC cell lines.

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Lanthanide metal-organic frameworks (Ln-MOFs) are promising for luminescence detection of volatile organic compound (VOC) vapors, but usually suffer from the silent or quenched Ln emission. Herein, we report a new dual-emissive Eu-MOF composed of the coordinatively unsaturated Eu clusters that afford abundant open metal sites to form a confined "binding pocket" to facilitate the preconcentration and recognition of VOCs. Single-crystal structural analyses reveal that specific analytes can replace the OH oscillators in the first coordination sphere of Eu and form a unique hydrogen-bonding second-sphere adduct tying adjacent Eu clusters together to minimize their nonradiative vibrational decay.

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The accumulation of free cholesterol in macrophage lysosomes significantly enhances atherogenesis. Our recent study demonstrated that the cluster of differentiation 38 (CD38)/nicotinic acid adenine dinucleotide phosphate (NAADP)/Ca signaling pathway plays a critical role in the efflux of lysosomal free cholesterol from macrophages in atherosclerosis. Niacin, known as nicotinic acid, is one of the oldest lipid-lowering medications showing unique anti-atherosclerotic activity.

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Many methods have been utilized to adjust the size of superatomic metal nanoclusters, while tuning the geometric conformations of specific nanoclusters is rare. Here, we demonstrate that conformation variation can be realized by slightly modifying the ligand under maintaining the nuclei number of metal atoms. A series of novel "double-chair" conformation Ln (Ln = Sm (), Eu (), Gd (), Tb (), and Dy ()) clusters were generated by replacing 3-formylsalicylic acid with 2,3-dihydroxybenzoic acid in the Ln nanocluster.

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Breast ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive ductal carcinoma (IDC). It is still unclear which DCIS will become invasive and which will remain indolent. Patients often receive surgery and radiotherapy, but this early intervention has not produced substantial decreases in late-stage disease.

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Background: Nerol (CHO), an acyclic monoterpene, naturally presents in plant essential oils, and is used widely in food, cosmetics and pharmaceuticals as the valuable fragrance. Meanwhile, chemical synthesis is the only strategy for large-scale production of nerol, and the disadvantages of chemical synthesis greatly limit the production and its application. These defects drive the interests of researchers shift to the production of nerol by eco-friendly methods known as biosynthesis methods.

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Article Synopsis
  • The process of separating ethylene (C2H4) from C hydrocarbons is complex and critical in the petrochemical industry, typically relying on energy-intensive cryogenic distillation methods.
  • Researchers have developed a new magnesium-based metal-organic framework (MOF) that can selectively adsorb ethylene and C hydrocarbons at high temperatures (up to 500 °C) with excellent stability.
  • This novel MOF not only efficiently separates ethylene from hydrocarbon mixtures under mild conditions but also offers a more sustainable and energy-efficient alternative to traditional separation techniques.
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Combining Ising-type magnetic anisotropy with collinear magnetic interactions in single-molecule magnets (SMMs) is a significant synthetic challenge. Herein we report a Dy[15-MC -5] (1-Dy) SMM, where a Dy ion is held in a central pseudo-D pocket of a rigid and planar Cu metallacrown (MC). Linking two Dy[15-MC -5] units with a single hydroxide bridge yields the double-decker {Dy[15-MC -5]} (2-Dy) SMM where the anisotropy axes of the two Dy ions are nearly collinear, resulting in magnetic relaxation times for 2-Dy that are approximately 200 000 times slower at 2 K than for 1-Dy in zero external field.

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Correction for 'Synthesis, characterization and anticancer mechanism studies of fluorinated cyclometalated ruthenium(ii) complexes' by Ya Wen et al., Dalton Trans., 2020, DOI: .

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Article Synopsis
  • Cancer cells' resistance to drugs like cisplatin poses a challenge for chemotherapy, prompting the development of new agents.
  • Seven cyclometalated ruthenium(ii) complexes with varying fluorine substitutions were created, showing greater cytotoxic effects against cisplatin-resistant cell line A549R compared to cisplatin.
  • The most effective complex, Ru1, has one fluorine atom, and works by entering cells, disrupting DNA and mitochondria functionality, ultimately triggering cell death through the caspase 3/7 pathway.
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Dye assemblies exhibit fascinating properties and performances, both of which depend critically on the mutual packing arrangement of dyes and on the supramolecular architecture. Herein, we engineered, for the first time, an intriguing chlorosome-mimetic 2D crystalline J-dimer lamellar structure based on halogenated dyes in aqueous media by employing two distinct orthogonal halogen-bonding (XB) interactions. As the only building motif, antiparallel J-dimer was formed and stabilized by single π-stacking and dual halogen⋅⋅⋅π interactions.

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The products of bacterial β-glucosidases with favorable cold-adapted properties have industrial applications. A psychrophilic β-glucosidase gene named bglG from subtropical soil microorganism Exiguobacterium sp. GXG2 was isolated and characterized by function-based screening strategy.

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The emerging pollutants antibiotic resistance genes (ARGs) are prevalent in aquatic environments such as estuary. Coastal mangrove ecosystems always serve as natural wetlands for receiving sewage which always carry ARGs. Currently, the research considering ARG distribution in mangrove ecosystems gains more interest.

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Although great achievements have been made in the synthesis of giant lanthanide clusters, novel structural models are still scarce. Herein, we report a giant lanthanide cluster Dy , constructed from [Dy (μ -OH) ] and [Dy (μ -O)(μ -OH) ] building blocks. As the largest known Dy cluster, the structure of Dy can be seen as arising from the fusion of two Dy clusters; these clusters can be isolated under various synthetic conditions and were characterized by single-crystal X-ray diffraction.

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Mangrove sediment microorganisms play a vital role in the energy transformation and element cycling in marine wetland ecosystems. Using metagenomics analysis strategy, we compared the taxonomic structure and gene profile of the mangrove and non-mangrove sediment samples at the subtropical estuary in Beibu Gulf, South China Sea. Proteobacteria, Bacteroidetes, and Firmicutes were the most abundant bacterial phyla.

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3-Deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS) is a key rate-limiting enzyme in aromatic amino acid anabolism. A new I-type DAHPS gene (aro1A) was identified in a metagenomic library from subtropical marine mangrove sediment. The gene encoded a polypeptide composed of 272 amino acids and had a maximum similarity of 52.

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A 3d-4f heterometallic metallacrown with formula of [EuCu(quinha)(sal)(py)]CFSO·py·3HO (1) (Hquinha = quinaldichydroxamic acid; Hsal = salicylaldehyde) has been synthesized. This complex shows field-induced slow magnetic relaxation via a Raman-like process, where studies of the isostructural {LuCu} (2) and {YCu} (3) complexes show that the slow dynamics mainly arise from the {Cu} S = 1/2 ground state rather than the Eu ion. However, the Eu ion enhances the relaxation rates of the {Cu} unit which likely arises from second-order effects in the formally diamagnetic F ground state of Eu.

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Mouse Embryonic Stem Cells (mESCs) are unique in their self-renewal and pluripotency. Hypothetically, mESCs model gestational stress effects or stresses of in vitro fertilization/assisted reproductive technologies or drug/environmental exposures that endanger embryos. Testing mESCs stress responses should diminish and expedite in vivo embryo screening.

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Here we examine recent evidence suggesting that many drugs and diet supplements (DS), experimental AMP-activated protein kinase (AMPK) agonists as well as energy-depleting stress, lead to decreases in anabolism, growth or proliferation, and potency of cultured oocytes, embryos, and stem cells in an AMPK-dependent manner. Surprising data for DS and drugs that have some activity as AMPK agonists in in vitro experiments show possible toxicity. This needs to be balanced against a preponderance of evidence in vivo that these drugs and DS are beneficial for reproduction.

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