Publications by authors named "Quantin C"
. Given the complexity of lung cancer surgery, this study aims to provide an overview of hospitals authorised to perform lung cancer surgery in France, and to assess their performance focusing on severe post-operative complications and 30-day in-hospital mortality based on the Clavien-Dindo classification (grade > 2). .
View Article and Find Full Text PDFBackground: Recent publications suggest that the threshold for validation of the learning curve is 25 procedures. The aim of this study was to evaluate this threshold using another rarely used method, based on a composite quality indicator.
Methods: We included all patients from the French medico-administrative database receiving robot-assisted surgery for lung cancer, with a focus on hospitals performing at least 25 procedures over the period 2019-2022.
Layered deposits are found on the plateaus surrounding the western portion of Valles Marineris, mantling the chasmata rims. These rim deposits exhibit intricate layering and are described as light-toned layered deposits (LLDs) in previous studies. Light-toned layered deposits are thought to be composed of pyroclastic ash that was emplaced during volcanic eruptions and later chemically altered.
View Article and Find Full Text PDFAims: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the risk of self-harming behaviours warrants further investigation. Here, we hypothesized that people with a history of hospitalization for self-harm may be particularly at risk of readmission in case of SARS-CoV-2 hospitalization.
Methods: We conducted a retrospective analysis based on the French national hospitalization database.
Objective: This retrospective, nationwide cohort study aimed to compare peri-procedural stroke or death within 30 days of the procedure (PPSD30) in patients who underwent carotid endarterectomy (CEA) or carotid stenting (CAS).
Methods: This retrospective cohort study used data from the French hospital database PMSI. All patients who underwent CEA or CAS between 2010 and 2019 in France were included.
Article Synopsis
- A study analyzed the impact of status epilepticus (SE) on in-hospital mortality and costs using a large French health insurance database from 2015 to 2019, focusing on patient demographics, causes, and healthcare expenses.
- Among 52,487 patients, 21.8% died in the hospital, with increasing mortality risks associated with older age, acute causes, tumors, and multiple comorbidities, while mechanical ventilation also significantly affected mortality.
- The average cost per SE hospitalization was around €6,517, highlighting a strong correlation between factors leading to higher mortality and increased healthcare costs, indicating a need for further research on long-term implications.
Article Synopsis
- * Parkinson's disease (PD) patients treated with l-DOPA show some protection against nAMD, but the exact mechanism was unclear until now.
- * Research indicates that l-DOPA enhances dopamine receptor D2 (DRD2) signaling, which may inhibit the harmful growth of blood vessels in the eye, suggesting that DRD2 agonists could be potential complementary treatments for nAMD.
Article Synopsis
- The study analyzes the use of the French National Health Data System (SNDS), which provides healthcare data for nearly the entire population of France, focusing on the trends in pharmacoepidemiological research based on this data.
- A systematic review of articles from 2012 to 2018 revealed an upward trend in published studies, with the majority focusing on drug utilization, safety, and effectiveness, and a notable concentration on medications for the nervous and cardiovascular systems.
- The findings suggest that while the SNDS is increasingly valuable for drug safety research, there is a need for more studies involving specific populations such as children, pregnant women, and the elderly, who are usually not represented in clinical trials.
Article Synopsis
- The study aimed to evaluate the effectiveness of two predictive models using the Epithor clinical database and a French hospital database to assess patient outcomes in hospitals.
- They split each database into training (70%) and validation (30%) sets and used metrics like the Brier score and AUC ROC to measure model performance.
- Results showed that while the hospital database model's predictive ability (AUC ROC of 0.8) was comparable to Epithor's (0.73), the hospital model missed key clinical factors like FEV1 and TNM stage, which were included in the Epithor model.
Introduction: While the factors commonly associated with an increased risk of child maltreatment (CM) were found to be increased during COVID-19, reports of actual maltreatment showed varying trends. Similarly, evidence regarding the impact of COVID-19 on CM within the European Cooperation on Science and Technology and Network Collaborative (COST) Action countries remains inconsistent. This scoping review aims to explore the extent and nature of evidence pertaining to CM within the countries affiliated with the Child Abuse and Neglect in Europe Action Network (Euro-CAN), funded by the COST.
View Article and Find Full Text PDFArticle Synopsis
- Physical abuse often begins early in life, making early diagnosis vital for protecting vulnerable infants, leading to this study assessing factors linked to the first hospitalization for such abuse in France.
- Researchers analyzed data from over 3.4 million newborns from 2009 to 2013, finding that 903 were hospitalized for physical abuse in their first year, with factors like male sex, prematurity, and multiple hospitalizations being significant risk indicators.
- The study reveals that having complementary universal health insurance is the strongest association with hospitalization for abuse, highlighting the need for targeted prevention strategies for at-risk groups, especially premature infants and those with frequent hospital visits.
Article Synopsis
- - The study examines the risk of bowel obstruction after incisional hernia repair (IHR) using intraperitoneal mesh (IPOM), which is the current standard treatment that can enhance quality of life but poses some risks.
- - Researchers compared a group of 815 patients who underwent laparoscopic IHR with IPOM to a control group of 1630 patients with similar surgical histories without IHR, tracking bowel obstruction incidents over five years.
- - Findings indicate that the IPOM group had a significantly higher rate of bowel obstruction (7.36%) compared to the control group (4.42%), suggesting that laparoscopic IPOM increases the risk of bowel obstruction post-surgery.
Article Synopsis
- The study aimed to track changes in quality indicators, specifically 30-day mortality and failure-to-rescue rates, for lung cancer surgery in France over 15 years, while examining potential influencing factors.
- It analyzed data from over 157,000 patients who underwent pulmonary resection from 2005 to 2020, focusing on various patient demographics, surgical techniques, and hospital characteristics.
- Results showed a decline in 30-day mortality from 2005 to 2020, a drop in failure-to-rescue rates, and highlighted that less use of pneumonectomies and the adoption of advanced surgical techniques significantly contributed to improved outcomes.
Article Synopsis
- Acute appendicitis is a common emergency surgery, and this study examines its potential link to an increased risk of developing colorectal cancer afterwards in France.
- Researchers analyzed data from nearly 230,349 patients with acute appendicitis between 2010 and 2015 and compared them to a control group of 460,698 patients with trauma to ensure accuracy.
- The findings revealed that patients treated for appendicitis had a significantly higher risk of being diagnosed with colon cancer, particularly in the first year post-appendicitis, with a notable increase in risk for those under 40 and for right-sided colon cancer.
Objective: To investigate the effect on major postpartum haemorrhage (PPH) of mode of conception, differentiating between naturally conceived pregnancies, fresh embryo in vitro fertilisation (fresh-IVF) and frozen embryo transfer (frozen-IVF).
Design: Retrospective cohort study.
Setting: The French Burgundy Perinatal Network database, including all deliveries from 2006 to 2020, was linked to the regional blood centre database.
Article Synopsis
- The minimally invasive approach (MIA) for lung cancer surgery has increased in use and is considered effective and safe across hospitals in France from 2013 to 2020.
- A total of 77,965 patients were analyzed, revealing a significant rise in MIA rates, reaching 50% by the 2019-2020 period, with some regional variability declining over time.
- Despite the overall increase in MIA adoption, variability remains notable between regions, with high-volume hospitals more likely to utilize this surgical technique compared to others.
Metal-rich fumes emitted during ore smelting contribute to widespread anthropogenic contamination. Environmental archives (such as lake sediments) record fallouts deposited on lake and terrestrial surfaces during ancient mining and smelting activities. However, very few is known about the potential buffering effect of soils upon which metal falls out, prior to be released through runoff and or/erosion, hence leading to pervasive contamination fluxes long after the ceasing of metallurgical activities.
View Article and Find Full Text PDF