Progress on Multifunction Enzyme-Activated Organic Fluorescent Probes for Bioimaging.

Bioimaging techniques are of increasing importance in clinical and related fields, which also have been successfully applied in the / imaging system. Due to the vital factor of enzymes in biological systems, enzyme-activated fluorophores, which could turn "on" the fluorescence signal from an "off" state, offer non-invasive and effective potential for the accurate bioimaging of particular cells, tissues, or bacteria. Comparing with the traditional imaging probes, enzyme-activated organic small fluorophores can visualize living cells within small animals with high sensitivity, high imaging resolution, non-invasiveness, and real-time feedback.