High expression of pituitary tumor-transforming gene-1 predicts poor prognosis in clear cell renal cell carcinoma.

Pituitary tumor-transforming gene-1 (PTTG1) is a recently identified oncogene involved in the progression of malignant tumors; however, the expression level of PTTG1 in clear cell renal cell carcinoma (ccRCC) and its potential value as a novel prognostic marker for ccRCC remains unclear. In this study, PTTG1 mRNA and protein levels were assessed in 44 paired ccRCC tissues and adjacent normal tissues by quantitative polymerase chain reaction (qPCR) and immunohistochemistry, respectively. Further immunohistochemical analysis was implemented in 192 samples of ccRCC to evaluate the associations between PTTG1 levels and the clinical characteristics in ccRCC.

[Effects of excess Mn on photosynthesis characteristics in cucumber under different light intensity].

By a solution culture experiment, this paper studied the effects of excess Mn on the growth, chlorophyll content, chlorophyll fluorescence parameters and photosynthesis of cucumber under different light intensity. The results indicated that excess Mn inhibited plant growth, which was more obvious under high light intensity than under low light intensity. The primary maximum photochemical efficiency of PSII (v/Fm), quantum efficiency of non-cyclic electron transport of PSII (phiPSII), and photochemical quenching (qP) were significantly decreased in excess Mn treatment under high light intensity, while no significant effects on Fv/Fm and qP were observed under low light intensity.