Publications by authors named "Quansheng Xu"

Article Synopsis
  • The study focuses on Evodiae fructus polysaccharide (EFP) and its purified fraction EFP-2-1, which has gastroprotective effects against alcohol-induced stomach lesions but needed further characterization.
  • EFP-2-1 was analyzed using advanced techniques and found to have a specific molecular structure, primarily consisting of rhamnose and other sugars, with a molecular weight of 7.3 kDa.
  • The fraction not only reduced gastric damage but also influenced inflammatory markers, activated specific metabolic pathways, and improved gut microbiota composition, suggesting its potential as a protective agent against alcohol-related gastric issues.
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Respiratory motion results in significant motion blur in thoracic and abdomen PET imaging. The extent of respiratory motion blur is mainly correlated with breathing amplitude, tumor size and location. In this paper we introduce a statistical study to quantitatively show the factors influencing the extent of respiratory motion blur in thoracic PET images.

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Respiratory motion results in significant motion blur in thoracic positron emission tomography (PET) imaging. Existing approaches to correct the blurring artifact involve acquiring the images in gated mode and using complicated reconstruction algorithms. In this paper, we propose a post-reconstruction framework to estimate respiratory motion and reduce the motion blur of PET images acquired in ungated mode.

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The synthesis and biochemical evaluation of novel cyanothiazolidine inhibitors of dipeptidyl peptidase 4 (DPP4) is described. Their main structural feature is a constrained bicyclic core that prevents the intramolecular formation of inactive cyclic species. The inhibitors show good to moderate biochemical potency against DPP4 and display distinct selectivity profiles towards DPP7, DPP8 and DPP9 depending on their substitution.

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