Publications by authors named "Quansen Hu"
Bladder cancer is a prevalent malignancy within the urinary system. Prior research has suggested that glutamine metabolism plays a crucial role in driving bladder cancer progression. However, the precise molecular mechanism governing glutamine metabolism in bladder cancer is still inadequately understood.
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- The study examined the role of lncRNA FOXD2-AS1 in clear cell renal cell carcinoma (ccRCC), revealing its high expression in cancer and its potential as a therapeutic target.
- Researchers identified that FOXD2-AS1 promotes ccRCC cell proliferation, migration, and invasion by upregulating EGLN3 expression through the recruitment of MYC to the EGLN3 promoter.
- Both in vitro and in vivo experiments confirmed the FOXD2-AS1/MYC/EGLN3 regulatory axis, indicating its significant influence on the progression of ccRCC, which may aid in improving prognostic strategies for patients.