PEGylated chitosan protected silver nanoparticles as water-borne coating for leather with antibacterial property.

Development of eco-labeled and effectively antibacterial coatings for final leather products has been desiderated both by industry and by consumers. Herein, PEGylated chitosan modified silver nanoparticles (PEG-g-CS@AgNPs) were prepared and characterized by UV-vis spectroscopy, transmission electron microscopy and dynamic light scattering. The antimicrobial activity of such silver nanoparticles was investigated against Gram-negative Escherichia coli (E.

Cell membrane-inspired polymeric micelles as carriers for drug delivery.

In cancer therapy, surface engineering of drug delivery systems plays an essential role in their colloidal stability, biocompatibility and prolonged blood circulation. Inspired by the cell membrane consisting of phospholipids and glycolipids, a zwitterionic phosphorylcholine functionalized chitosan oligosaccharide (PC-CSO) was first synthesized to mimic the hydrophilic head groups of those amphipathic lipids. Then hydrophobic stearic acid (SA) similar to lipid fatty acids was grafted onto PC-CSO to form amphiphilic PC-CSO-SA copolymers.