Publications by authors named "Quan-Qing Wen"
[Effect of notch signaling on differentiation of rat marrow mesenchymal stem cells into neurons induced by fasudil hydrochloride].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
November 2010
Objective: To investigate the effect of notch signaling on differentiation of rat bone marrow mesenchymal stem cells (MSCs) into neurons induced by fasudil hydrochloride.
Methods: The experiments were divided into non-transfected group, transfected group (transfected with Rn-Notch1-siRNA), positive control group (transfected with Rn-MAPK-1 Control siRNA) and negative control group (transfected with negative control siRNA). Fasudil hydrochloride induced MSCs differentiating into neurons.
[Expression of microRNA in neonatal rats with hypoxic-ischemic brain damage].
Zhongguo Dang Dai Er Ke Za Zhi
May 2010
Objective: To study the changes of microRNA expression in cortex tissues in neonatal rats with hypoxic-ischemic brain damage (HIBD)and the possible roles of microRNA in the pathogenesis of HIBD. METHODS Rat HIBD model was prepared. The cortex tissues were obtained 14 days after the HIBD event.
View Article and Find Full Text PDF[Effects of DSCAM on differentiation of rat marrow mesenchymal stem cells into neurons in vitro].
Zhongguo Dang Dai Er Ke Za Zhi
June 2009
Objective: To study the effects of Down syndrome cellular adhesion molecule (DSCAM) on differentiation of rat marrow mesenchymal stem cells (MSCs) into neurons in vitro.
Methods: MSCs from Sprague-Dawley rats were induced into neurons by baicalin. The expression of DSCAM before and after induction was evaluated by immunocytochemical staining and Western blot assay.