Publications by authors named "Quan-Bo Liu"

Article Synopsis
  • The study investigated the clinical features of children infected with COVID-19 compared to other respiratory infections like RSV, Influenza, and adenovirus, focusing on symptoms and cytokine profiles.
  • It involved 20 COVID-19 positive hospitalized children, 58 with other acute respiratory tract infections, and 20 healthy controls, with data collected on clinical symptoms and blood test results.
  • Findings revealed that COVID-19 patients were older and had milder symptoms than those with other infections, along with notable differences in immune response indicated by cytokine levels.
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Objective: To study the clinical features of infection in children with secondary immunodeficiency disease (SID) versus primary immunodeficiency disease (PID).

Methods: A retrospective analysis was performed on the medical data of children with immunodeficiency and infection (36 children with SID and 52 with PID) and 108 children with infection but without immunodeficiency (control group).

Results: The onset age in the PID group was significantly lower than those in the control and SID groups ( < 0.

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Objectives: Linezolid (LNZ) has recently been listed by the World Health Organization (WHO) as a Group A agent for the treatment of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) in longer regimens (18-20 months). However, little is known about the safety of LNZ in longer TB treatment regimens in children.

Methods: Here we report 31 children who received LNZ treatment for drug-resistant tuberculosis (DR-TB) and extensive tuberculosis in the Children's Hospital of Chongqing Medical University, China, during September 2016 to March 2019.

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Background: Herpangina is a common infectious disease in childhood caused by an enterovirus. This consensus is aiming to standardize and improve herpangina prevention and clinical diagnosis.

Methods: The Subspecialty Group of Infectious Diseases, the Society of Pediatric, Chinese Medical Association and Nation Medical Quality Control Center for Infectious Diseases gathered 20 experts to develop the consensus, who are specialized in diagnosis and treatment of herpangina.

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Hepatitis B virus (HBV) study is hampered by lacking of idea cell model which support effective HBV infection and meanwhile recapitulate hepatocyte biology function in vivo. In this study, we developed decellularized human liver scaffolds for cell culture and further applied for HBV infection. As a result, primary human hepatocytes (PHHs) engrafted into liver scaffolds and maintained differentiation with stable albumin secretion and liver-specific gene expression.

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Article Synopsis
  • A 64-year-old woman with a long history of nasopharyngeal carcinoma was diagnosed with NK/T-cell lymphoma after presenting with swollen lymph nodes and persistent fever.
  • During her treatment, she developed SIADH, which resulted in low sodium levels due to excessive antidiuretic hormone secretion.
  • Despite treatment to correct her sodium levels, her health deteriorated, leading to severe infections and ultimately respiratory failure; this case highlights the need for careful monitoring of electrolytes in similar lymphoma patients.
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Background: Hand-foot-and-mouth disease (HFMD) is a disease that had similar manifestations to chickenpox, impetigo, and measles, which is easy to misdiagnose and subsequently causes delayed therapy and subsequent epidemic. To date, no study has been conducted to report the clinical and epidemiological characteristics of atypical HFMD.

Methods: 64 children with atypical HFMD out of 887 HFMD children were recruited, stool was collected, and viral VP1 was detected.

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