Haploidentical parental hematopoietic stem cell transplantation in pediatric refractory Langerhans cell histiocytosis.

Children with MS-LCH that fail to respond to conventional chemotherapy have poor outcomes. HSCT represents a potential salvage approach. It has been applied in over 50 cases in recent years.

2-[3-Acetyl-5-(2-chloro-3-pyrid-yl)-2-methyl-2,3-dihydro-1,3,4-oxadiazol-2-yl]-4-fluoro-phenyl acetate.

In the title compound, C(18)H(15)ClFN(3)O(4), the dihedral angle between the substituted pyridine ring and the oxadiazo-line ring is 9.73 (19)° and the acyl group is coplanar with the oxadiazo-line ring [O-C-N-C torsion angle = -2.1 (3)°].