Fe, Rather Than Soil Organic Matter, as a Controlling Factor of Hg Distribution in Subsurface Forest Soil in an Iron Mining Area.

To identify whether the iron (Fe) mining area in the Jiulongjiang River basin (JRB) has an influence on the mercury in the forest soil, the spatial distribution patterns of mercury's behavior on different controlling factors were analyzed, and a potential ecological risk assessment was done. A total of 107 soil samples were collected from two forest soil profiles, one profile near the Fe mining area and the other far from it. The soil near the mining area had a moderate potential ecological risk with high Fe content rich in the upper layer of soil (<70 cm), whereas soil collected far from the mining area had a low potential ecological risk.

Fragment-based discovery of flexible inhibitor targeting wild-type acetohydroxyacid synthase and P197L mutant.

Background: Intensifying weed resistance has challenged the use of existing acetohydroxyacid synthase (AHAS)-inhibiting herbicides. Hence, there is currently an urgent requirement for the discovery of a new AHAS inhibitor to effectively control AHAS herbicide-resistant weed species produced by target mutation.

Results: To combat weed resistance caused by AHAS with P197L mutation, we built a structure library consisting of pyrimidinyl-salicylic acid derivatives.

Icariin prevents oestrogen deficiency-induced alveolar bone loss through promoting osteogenesis via STAT3.

Objectives: Alveolar bone osteoporosis has attracted more and more attention because of its profound impact on stomatognathic function and treatment, but current treatments have not been targeted to alveolar bone and might even cause severe side effects. Thus, identifying the effects of anti-osteoporosis agents on alveolar bone is essential. Icariin ameliorates metabolic dysfunction of long bones, but its effects on alveolar bone remain unclarified.

Peanut Leaf-Inspired Hybrid Metal-Organic Framework with Humidity-Responsive Wettability: toward Controllable Separation of Diverse Emulsions.

Damage to the responsive superwetting material by external stimuli during the responsive process has been a ticklish question in recent years. We overcome this barrier by imitating a peanut leaf and designing a humidity-responsive MIL-100 (Fe)/octadecylamine-coated stainless steel mesh (HR-MOS). Such a material shows superhydrophilicity when ambient humidity is higher than saturated humidity, while it shows superhydrophobicity and high adhesion to water when ambient humidity is lower than saturated humidity.

Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.

Mucosal barrier immunity is essential for the maintenance of the commensal microflora and combating invasive bacterial infection. Although immune and epithelial cells are thought to be the canonical orchestrators of this complex equilibrium, here, we show that the enteric nervous system (ENS) plays an essential and non-redundant role in governing the antimicrobial protein (AMP) response. Using confocal microscopy and single-molecule fluorescence in situ mRNA hybridization (smFISH) studies, we observed that intestinal neurons produce the pleiotropic cytokine IL-18.

Correction to: Ghrelin Fights against Titanium Particle-Induced Inflammatory Osteolysis through Activation of β-Catenin Signaling Pathway.

The original version of this article was published with incorrect Fig. 1B. The correct Fig.

Oxidative Oligomerization of Phenolic Endocrine Disrupting Chemicals Mediated by Mn(III)-L Complexes and the Role of Phenoxyl Radicals in the Enhanced Removal: Experimental and Theoretical Studies.

Soluble manganese(III), stabilized by ligands as Mn(III)-L complexes, are ubiquitous in natural waters and wastewaters and can potentially serve as both the oxidant and reductant in one-electron transfer reactions with organic contaminants. In this study, the oxidative transformations of 14 phenolic endocrine disrupting chemicals (EDCs) by in situ-formed Mn(III)-L complexes, generated from irradiated water containing Mn(II) and humic acid, were investigated. The pseudo-first-order rate constants (, h) of these phenols varied from 1.

A Glance at the Nuclear Envelope Spectrin Repeat Protein 3.

Nuclear envelope spectrin repeat protein 3 (nesprin-3) is an evolutionarily-conserved structural protein, widely-expressed in vertebrate cells. Along with other nesprin family members, nesprin-3 acts as an essential component of the linker of nucleoskeleton and cytoskeleton (LINC) complex. Naturally, nesprin-3 shares many functions with LINC, including the localization of various cellular structures and bridging of the nucleoskeleton and cytoskeleton, observed .

Spatial Variation and Controlling Factors of H and O Isotopes in Lancang River Water, Southwest China.

Climate changes and other human activities have substantially altered the hydrological cycle with respect to elevation. In this study, longitudinal patterns in the stable isotopic composition (δH and δO) of Lancang River water, originating from the Qinghai-Tibetan Plateau, are presented, and several controlling factors in the wet season are hypothesized. Lancang River water δH (-145.

Stepwise Adipogenesis of Decellularized Cellular Extracellular Matrix Regulates Adipose Tissue-Derived Stem Cell Migration and Differentiation.

Microenvironmental factors can modulate the cellular status of adipose tissue-derived stem cells (ASCs). In response to microenvironmental changes, cells can remodel extracellular matrix (ECM) proteins, which play an important role in regulating cell behaviors. During adipogenic differentiation, ECM components secreted from ASCs remodel dramatically.

MicroRNA-451 is downregulated in the follicular fluid of women with endometriosis and influences mouse and human embryonic potential.

Background: Previous work demonstrated that there are numerous miRNAs in human follicular fluids, some of which are associated with reproductive diseases. In the current study, we sought to determine whether microRNAs (miRNAs) in the follicular fluid (FF) are differentially expressed between women with and without endometriosis and to uncover the association of miRNAs with the oocyte and embryonic development potential.

Methods: FF was harvested from 30 women with endometriosis and 30 women without who underwent in vitro fertilization treatment at the University Hospital between February and December 2016.

Visible light and fulvic acid assisted generation of Mn(III) to oxidize bisphenol A: The effect of tetrabromobisphenol A.

Bisphenol A (BPA) and tetrabromobisphenol A (TBBPA), endocrine disrupting compounds (EDCs), are of increasing concerns for many years. This paper presents the elimination of BPA under visible light (VL) (λ ≥ 420 nm) irradiated solutions containing fulvic acid (FA) and MnSO (Mn(II)), and examines the possible effects of TBBPA on the transformation of BPA. After 72 h of reaction time, the removal efficiency of BPA in the studied system was 69%.

Identification of breast cancer-related circRNAs by analysis of microarray and RNA-sequencing data: An observational study.

Background: An increasing number of studies indicate that circular RNAs (circRNAs) participate in tumorigenesis. The aim of this study was to elucidate the regulatory mechanisms of circRNAs in breast cancer based on the construction of the circRNA-related ceRNA network.

Methods: The expression profiles of circRNAs, miRNAs, and mRNAs were obtained from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases.

The Mercury Behavior and Contamination in Soil Profiles in Mun River Basin, Northeast Thailand.

To determine the geochemical characteristics and contamination of soil mercury in the Mun River basin, northeast Thailand, the vertical mercury distribution patterns and mercury contamination levels in six soil profiles under different land uses are studied. A total of 240 soil samples collected from agricultural land, abandoned agricultural land, and woodland were analyzed by an RA-915M mercury analyzer to determine the total mercury (THg) content, which ranged from 0.13 to 69.

Scutellarin suppresses cartilage destruction in osteoarthritis mouse model by inhibiting the NF-κB and PI3K/AKT signaling pathways.

Osteoarthritis (OA), a common and severe disease, is predominantly characterized by cartilage destruction, which results in the degeneration of joint surfaces. Nowadays, it is accepted that TNFα plays a critical role in OA. Scutellarin, the main bioactive flavonoid glycoside extracted form Erigeron breviscapus, has been reported to exert positive effects on anti-inflammatory reactions.

The Transareola Endoscopic Approach Yields Adequate Oncological Dissection as Open Approach in the Treatment of Papillary Thyroid Carcinoma.

Objective: This study aimed to evaluate and discuss whether the transareola endoscopic surgery has similar outcome outcomes to open surgery in the treatment of papillary thyroid carcinoma (PTC).

Method: A total of 102 patients with PTC were enrolled in this study. Among them, 53 patients were treated by transareola endoscopic surgery (endoscopic group) and 49 patients were treated by open surgery (open group).

Application of coagulation-ultrafiltration-nanofiltration in a pilot study for Tai Lake water treatment.

In this study, the inline coagulation was combined with ultrafiltration and nanofiltration (UF-NF) in a pilot study for Tai Lake water treatment. The results showed that the combination process was very effective for Tai Lake water treatment in terms of organic removal and membrane fouling control. With inline coagulation, no irreversible membrane fouling was observed for either UF or NF at fluxes of 65-90 and 22-26 L/(m  hr), respectively.

On the fracture mechanisms of nacre: Effects of structural orientation.

The nacre of mollusk shells is distinguished by an exceptional mechanical efficiency which is derived essentially from its lamellar structure and frequently acts as a source of inspiration for the development of biomimetic materials. The structure and mechanical properties of nacre have been intensively investigated with a special focus on its toughening strategies; nevertheless, the fracture mechanisms, more specifically the critical stress/strain conditions for the failure of nacre, and the effects of structural orientation and hydration state remain largely unexplored. Here uniaxial compression tests were performed on nacre of both dry and hydrated states with different off-axis angles, i.

Practical multi-class event classification approach for distributed vibration sensing using deep dual path network.

Influenced by severe ambient noises and nonstationary disturbance signals, multi-class event classification is an enormous challenge in several long-haul application fields of distributed vibration sensing technology (DVS), including perimeter security, railway safety monitoring, pipeline surveillance, etc. In this paper, a deep dual path network is introduced into solving this problem with high learning capacity. The spatial time-frequency spectrum datasets are built by utilizing the multidimensional information of DVS signal, especially the spatial domain information.

A homozygous mutation in CMAS causes autosomal recessive intellectual disability in a Kazakh family.

Intellectual disability (ID) describes a wide range of serious human diseases caused by defects in central nervous system development and function. Some mutant genes have been found to be associated with these diseases, but not all cases can be explained, thus suggesting that other disease-causing genes have not yet been discovered. Sialic acid is involved in a number of key biological processes, including embryo formation, nerve cell growth, and cancer cell metastasis, and very recently it has been suggested that N-acetylneuraminic acid synthase-mediated synthesis of sialic acid is required for brain and skeletal development.

Fabrication of Triethylenetetramine Terminal Hyperbranched Dendrimer-Like Polymer Modified Silica Gel and Its Prominent Recovery Toward Au (III).

To further increase the quantity and density of functional groups on adsorbent, terminal triethylenetetramine hyperbranched dendrimer-like polymer modified silica-gel (SG-TETA and SG-TETA2) was synthesized. The hyperbranched dendrimer-like polymer was successfully introduced onto silica gel and new cavities were formed, which was demonstrated by FTIR, SEM, and BET. The highest adsorption capacities of SG-TETA and SG-TETA2 obtained from Langmuir model toward Au(III) were 2.

New Insights into the Decomposition Behavior of NHHSO on the SiO-Decorated SCR Catalyst and Its Enhanced SO-Resistant Ability.

This article illustrates the detailed decomposition behavior of NHHSO on the TiO and TiO-SiO supports, along with the effect of SiO addition on the sulfur resistance of the corresponding VO-based catalysts. For TiO support, sulfate species selectively occupied its surface basic hydroxyl groups, while Si-OH groups functioned as the main sites for the accommodation of NHHSO over the TiO-SiO mixed support, enabling its surface sulfate species with higher thermal stability. Compared with NH on the TiO surface, NH on the TiO-SiO mixed support was much easier to be consumed during the heating process, hence causing some variations in the decomposition behavior of NHHSO.

Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

An Amendment to this paper has been published and can be accessed via a link at the top of the paper.

Oxidation of flumequine in aqueous solution by UV-activated peroxymonosulfate: Kinetics, water matrix effects, degradation products and reaction pathways.

The degradation of flumequine (FLU) in aqueous solution by ultraviolet (UV)-activated peroxymonosulfate (PMS) was investigated in this work. Under the conditions of [PMS]:[FLU] = 1:1, T = 25 ± 2 °C, pH = 7.0 ± 0.