Publications by authors named "Qizhen Peng"
Article Synopsis
- Researchers used various methods, including immunohistochemical staining and genetic analysis, to evaluate the effectiveness of alisertib and lenvatinib against liver cancer (HCC).
- They found that the combination treatment significantly reduced cancer cell growth and migration more than either drug alone, and it also caused more DNA damage in cancer cells.
- The study suggests that combining alisertib with lenvatinib could be a promising strategy for improving treatment outcomes in HCC patients.
Owing to the high morbidity and mortality of cardiovascular diseases resulting from atherosclerosis, developing specific noninvasive diagnostic methods to distinguish vulnerable atherosclerotic plaques becomes urgent and mandatory. Herein, scavenger receptors AI (SR-AI), a secreted biomarker associated with foam macrophages, was selected as a target for identifying vulnerable plaques. A dual-modality imaging probe (PP1-Au@GSH@Gd NCs) was constructed by covalently attaching a peptidic SR-AI ligand, PP1 to gadolinium-integrated gold nanoclusters, which exhibited remarkably improved fluorescence signal and longitudinal relaxivity with highly loaded Au and Gd species.
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