Publications by authors named "Qizhen Hu"
Article Synopsis
- The study examines how glucagon secretion in type 1 diabetes (T1D) patients relates to their remaining beta cell functions, focusing on the differences between individuals with low and high C-peptide levels.
- It involved 43 T1D adults and 24 healthy controls, measuring various hormone levels during a meal tolerance test to assess glucagon response over time.
- Results indicated that T1D patients had altered glucagon levels compared to controls, with those having lower C-peptide showing a significant increase in glucagon response, which correlated with greater post-meal glucose levels.
High Residual β-cell Function in Chinese Patients With Autoimmune Type 1 Diabetes.
J Clin Endocrinol Metab
May 2022
Article Synopsis
- Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by the destruction of pancreatic β cells, and this study focused on understanding β-cell function in Chinese T1D patients compared to previous studies on Caucasians.
- The research involved 446 T1D participants, assessing their β-cell function through glucose tolerance tests, and examining various clinical factors and genetic data related to β-cell activity.
- Findings revealed that a significant majority of the patients had detectable C-peptide levels, indicating residual β-cell function, especially in those diagnosed at older ages, suggesting potential for therapeutic strategies to enhance β-cell function in this population.*