Publications by authors named "Qiyue Yan"
Article Synopsis
- Lactylation (Kla) is a newly found chemical modification that comes from lactate and is important for many cell functions, but its role in hypertrophic scar formation isn't well understood.
- Researchers identified 1023 lactylation sites from 338 nonhistone proteins in hypertrophic scars and normal skin, as well as 2008 proteins overall in these tissues.
- The study found that lactylation mainly affects genes related to ribosome function and glycolysis, with 14 specific lactylation sites significantly increased in hypertrophic scars, suggesting that lactylation could help regulate processes connected to scar formation.
TRP Ion Channels in Immune Cells and Their Implications for Inflammation.
Int J Mol Sci
February 2024
The transient receptor potential (TRP) ion channels act as cellular sensors and mediate a plethora of physiological processes, including somatosensation, proliferation, apoptosis, and metabolism. Under specific conditions, certain TRP channels are involved in inflammation and immune responses. Thus, focusing on the role of TRPs in immune system cells may contribute to resolving inflammation.
View Article and Find Full Text PDF