Publications by authors named "Qiyuan Hao"

Article Synopsis
  • This study explores the rare condition of pneumatosis cystoides intestinalis (PCI) in a patient with granulomatosis with polyangiitis (GPA), highlighting its clinical and imaging features.
  • The case involves a 71-year-old woman with GPA who showed no symptoms of PCI despite CT scans indicating gas in her colon wall, stressing the need for careful monitoring in similar patients.
  • The findings suggest that PCI can occur in GPA patients without typical symptoms, pointing to a need for further investigation into the mechanisms and treatment of this unusual complication.
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Background: To systematically describe clinical characteristics and investigate factors associated with COVID-19-related infection, hospital admission, and IgG4-related disease relapse in IgG4-RD patients.

Methods: Physician-reported IgG4-RD patients were included in this retrospective study. Using multivariable logistic regression analysis to determine factors for primary outcome (COVID-19-related IgG4-RD relapse) and secondary outcome (COVID-19-related infection and hospital admission).

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Objectives: Gout is characterized by hyperuricemia and recurrent inflammatory episodes caused by intra-articular crystal deposition of monosodium urate (MSU). There is a clear relationship between gout and metabolic syndrome. Recent evidence indicates that perforin plays a role in regulating glucose homeostasis and provides protection in diet-induced non-alcoholic steatohepatitis models.

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Article Synopsis
  • - This study investigated how polysaccharides (LBP) can protect intestinal health and microbiota in mice suffering from ulcerative colitis induced by dextran sulfate sodium (DSS) over 8 weeks.
  • - Mice treated with LBP showed better health indicators, such as increased body weight and colon length, reduced inflammation, and enhanced expression of protective proteins compared to those receiving DSS alone.
  • - LBP not only boosted beneficial probiotic levels but also reduced harmful bacteria and increased short-chain fatty acid production, indicating its potential as a prebiotic treatment for ulcerative colitis.
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Immunoglobulin G4 (IgG4)-related disease is a chronic fibroinflammatory disease mediated by immune disorders. Given the challenging clinical diagnosis and treatment, knowledge of the pathogenesis of IgG4-related disease is important. The typical elevation of serum IgG4 concentrations and infiltration of IgG4-positive plasma cells in the involved tissues indicate the involvement of B lymphocytes in the pathogenesis of IgG4-related disease.

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Introduction: Colorectal cancer holds a high morbidity and mortality rate. As a common method for colorectal cancer detection, colonoscopy has difficulty in passing through the malignant stenosis in patients with obstructive colorectal cancer, which results in incomplete detection and missed diagnosis. The missed synchronous lesions increase the risk of metachronous cancer.

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