Publications by authors named "Qixuan Cheng"
Molecular mechanism governing RNA-binding property of mammalian TRIM71 protein.
Sci Bull (Beijing)
January 2024
Article Synopsis
- TRIM71 is an RNA-binding protein with functions in cell cycle regulation and stem cell self-renewal, and interacts with the long noncoding RNA Trincr1 to modulate the FGF/ERK signaling pathway in mouse embryonic stem cells.
- The study identifies a specific RNA motif recognized by mTRIM71 in Trincr1 and details the crystal structure of its NHL domain bound to this RNA, highlighting an essential adenosine in the interaction.
- Key amino acid residues in mTRIM71 are identified as crucial for RNA binding, and mutations can hinder its ability to attach to hairpin RNAs and mRNAs linked to cell cycle regulation, providing insights into TRIM71-related
Complete mitochondrial genomes of three mitten crabs, Eriocheir sinensis, E. hepuensis, and E. japonica.
Mitochondrial DNA A DNA Mapp Seq Anal
September 2016
Article Synopsis
- The study focuses on the taxonomic classification of three mitten crab species: Eriocheir sinensis, E. hepuensis, and E. japonica, which has been previously debated.
- Researchers analyzed the complete mitochondrial genomes (mitogenomes) of these crabs, revealing 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and 1 control region, indicating a conserved gene organization.
- Nucleotide variations and differing tandem repeats in the control regions among the species were discovered, offering insights into their evolutionary history and taxonomic relationships.
Article Synopsis
- Differentiation in phenotypic traits (P(ST)) and neutral molecular markers (F(ST)) in populations of Chinese mitten crab and Hepu mitten crab was studied in the Minjiang River, revealing significant differences in 11 phenotypic traits between populations sampled in 2009 and 2010.
- The 2009 population showed higher expected heterozygosity than the 2010 population, while other genetic measures like allele richness and observed heterozygosity did not show significant changes.
- The study found that stabilizing selection favored one trait, while the other traits indicated directional selection, contributing valuable insights into the molecular evolution of mitten crabs and setting a reference for comparisons in other aquatic species.