Full utilization of Flammulina filiformis spent mushroom substrate for sustainable production of oil/water separation bacterial nanocellulose composite with high liquid flux and seperation efficiency.

Bacterial nanocellulose (BNC) is a promising material for oily wastewater separation due to its hydrophilic and nanometer-scale porous structure. However, its application is constrained by high production costs. This study explores the utilization of underutilized Flammulina filiformis spent mushroom substrate (Ff-SMS) to produce BNC cost-effectively.

Quantitative analysis of charge transfer plasmons in silver nanocluster dimers using semiempirical methods.

Plasmonic metal nanoclusters are widely used in chemistry, nanotechnology, and biomedicine. In metal nanocluster dimers, coupling of the plasmons leads to the emergence of two distinct types of modes: (1) bonding dipole plasmons (BDP), which occurs when charge oscillates synchronously within each nanocluster, and (2) charge transfer plasmons (CTP), which occurs when charge oscillates between two conductively linked nanoclusters. Although TDDFT-based modeling has uncovered some trends in these modes, it is computationally expensive for large dimers, and quantitative analysis is challenging.

Multistage stabilization of Cd, Pb, Zn, Cu and As in contaminated soil by phosphorus-coated nZVI layered composite materials: characteristics, process and mechanism.

This study developed a shell-like slow-release material, PF@ST/Fe-0.5, by encapsulating nanoscale zero-valent iron composites (NZC) with phosphate fertilizer (PF) and a starch binder (ST). The material dissolved in soil in stages, first releasing P and Ca to increase the soil pH from 4.

Effect of addition of γ-poly glutamic acid on bacterial nanocellulose production under agitated culture conditions.

Background: Bacterial nanocellulose (BNC), a natural polymer material, gained significant popularity among researchers and industry. It has great potential in areas, such as textile manufacturing, fiber-based paper, and packaging products, food industry, biomedical materials, and advanced functional bionanocomposites. The main current fermentation methods for BNC involved static culture, as the agitated culture methods had lower raw material conversion rates and resulted in non-uniform product formation.

Geographic distribution of general industry payments to advanced-practice clinicians.

Following the recent expansion of the Open Payments program to include advanced-practice clinicians (APCs) as covered recipients, we characterized the geographical distribution of general industry payments to nurse practitioners and physician assistants using the Open Payments database. The number and dollar value of payments, as well as the average and median payment amount earned per provider, varied by state. However, a significantly higher proportion of APCs received payments in states with more restrictive scope-of-practice laws.

The Effect of Notch and Molecular Weight on the Impact Fracture Behavior of Polycarbonate.

The impact protection applications of polycarbonate (PC) products are gradually increasing. Due to the high sensitivity of PC to notches, research on notch impacts has become very important. In this paper, the impact performance of PC with two different molecular weights under different notch states was investigated.

CD9 shapes glucocorticoid sensitivity in pediatric B-cell precursor acute lymphoblastic leukemia.

Resistance to glucocorticoids (GC), the common agents for remission induction in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL), poses a significant therapeutic hurdle. Therefore, dissecting the mechanisms shaping GC resistance could lead to new treatment modalities. Here, we showed that CD9- BCP-ALL cells were preferentially resistant to prednisone and dexamethasone over other standard cytotoxic agents.

Comparison of industry payments to psychiatrists and psychiatric advanced practice clinicians in the USA, 2021: a cross-sectional study.

Objectives: To compare industry payment patterns among US psychiatrists and psychiatric advanced practice clinicians (APCs) and determine how scope of practice laws has influenced these patterns.

Design: Cross-sectional study.

Setting: This study used the publicly available US Centers for Medicare and Medicaid Services Sunshine Act Open Payment database and the National Plan and Provider Enumeration System (NPPES) database for the year 2021.

Co-production of pigment and high value-added bacterial nanocellulose from biomass with improved efficiency of enzymatic saccharification and fermentation.

This study evaluated the co-production of pigment and bacterial nanocellulose (BNC) from biomass. The extraction of the beet red pigment reduced the salts and flavonoids contents by 82.7%-100%, promoting the efficiencies of enzymatic saccharification of the biomass and the fermentation of BNC from the hydrolysate.

Synchronous stabilization of Pb, Zn, Cd, and As in lead smelting slag by industrial solid waste.

In order to prevent heavy metal (HM) pollution from lead smelting slag (LSS) to the surrounding environment, this work investigated the feasibility, influencing factors, and mechanisms of using industrial solid waste such as fly ash (FA), oil sludge pyrolysis residue (PR), and steel slag (SS) as remediation amendments. The results demonstrated that the stabilization process was influenced by the material dosage, water content, and LSS particle size. Compared to single materials, the combination amendment PR2FA1 (with a mass ratio of PR to FA as 2:1) exhibited the best stabilization effect, simultaneously reducing the leaching concentrations of As, Zn, Cd, and Pb in LSS to 0.

Building Coarse to Fine Convex Hulls With Auxiliary Vertices for Palette-Based Image Recoloring.

Constructing a convex hull for the pixel colors of an image by viewing them as 3D points can extract a set of palette colors for the image, then image recoloring can be achieved by modifying the palette colors. For better recoloring effect, the convex hull should contain more pixels (inclusive) and be more compact. Otherwise, reconstruction error would occur or the extracted palette color would be less representative, yielding wrong recoloring results or less effective edit.

Bonding and Acidity of the Formal Hydride in the Prototypical Au (PPh ) H Nanocluster.

The role of hydrogen atoms as surface ligands on metal nanoclusters is of profound importance but remains difficult to directly study. While hydrogen atoms often appear to be incorporated formally as hydrides, evidence suggests that they donate electrons to the cluster's delocalized superatomic orbitals and may consequently behave as acidic protons that play key roles in synthetic or catalytic mechanisms. Here we directly test this assertion for the prototypical Au (PPh ) H nanocluster, formed by addition of a hydride to the well-characterized Au (PPh ) .

The immunogenic involvement of miRNA-492 in mycoplasma pneumoniae infection in pediatric patients.

Objective: This study aimed to evaluate the role of miRNA-492 in the progression of mycoplasma pneumoniae (MP) infection in pediatric patients.

Methods: Forty-six children admitted to the present study's hospital and diagnosed with mycoplasma pneumonia were recruited as the study group from March 2018 to August 2019, and 40 healthy children were selected as the control group.

Results: The expression levels of miRNA-492, TNF-α, IL-6 and IL-18 in the study group were significantly higher than those in the control group (p < 0.

Parametrization of the PM7 Semiempirical Quantum Mechanical Method for Silver Nanoclusters.

Semiempirical quantum mechanical methods (SEQMs) are widely used in computational chemistry because of their low computational cost, but their accuracy depends on the quality of the parameters. The neglect of diatomic differential overlap method PM7 is among the few SEQMs that contain parameters for Ag, but the experimental reference data was insufficient to obtain reliable parameters in the original parametrization. In this work, we reparametrize the PM7 parameters for Ag to accurately reproduce the ground-state potential energy surfaces of Ag clusters.

Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine.

Unlabelled: Despite the expanding portfolio of targeted therapies for adults with acute myeloid leukemia (AML), direct implementation in children is challenging due to inherent differences in underlying genetics. Here we established the pharmacologic profile of pediatric AML by screening myeloblast sensitivity to approved and investigational agents, revealing candidates of immediate clinical relevance. Drug responses ex vivo correlated with patient characteristics, exhibited age-specific alterations, and concorded with activities in xenograft models.

Carbonaceous material prepared by pyrolysis of refinery oily sludge for removal of flotation collectors in wastewater.

The carbonaceous material (CM) prepared by refinery oily sludge was proposed to remove flotation collectors, butyl xanthate (BX), and diethyldithiocarbamate (DDTC) in synthetic wastewater. The effects of the CM on removal efficiency, adsorption kinetics, and isotherms were experimentally carried out. The surface structure and composition of CM were characterized by BET isotherm, XRD, and SEM-EDS, and the concentration of BX and DDTC was tested by UV-VIS spectrometer.

AZI2 positively regulates the induction of type I interferon in influenza-trigger pediatric pneumonia.

5-azacytidine-induced protein 2 (AZI2) is known to have a crucial role in antiviral innate immunity. This study aims to explore the roles of AZI2 in influenza-trigger pediatric pneumonia and its molecular mechanism. qPCR and immunoblotting assays were used to determine the levels of target genes and proteins.

Symbiotic composite composed of MoS and pelagic clay with enhanced disinfection efficiency.

Molybdenum disulfide (MoS) has attracted increasing attention as a promising photocatalyst. In addition to its application in photocatalytic hydrogen production and pollutant degradation, MoS is also used in water disinfection. However, its poor disinfection performance limits its practical utility.

Stem cell therapy for pulmonary arterial hypertension: An update.

Pulmonary arterial hypertension (PAH) remains a deadly disease, and there currently is no cure for this life-threating medical problem. The average lifespan is about 5 to 7 years after diagnosis of PAH. Therefore, a conceptual breakthrough to develop new therapeutic strategies for PAH is urgently needed.

Hydrothermal Synthesis of 1T-MoS/Pelagic Clay Composite and Its Application in the Catalytic Reduction of 4-Nitrophenol.

Pelagic clay is an emerging marine resource with strong hydrophilicity, fine particles and a large specific surface area. In this work, a 1T-MoS/pelagic clay composite was fabricated by hydrothermal synthesis. In the composite, 1T-MoS nanosheets are evenly dispersed on the surface of the clay minerals, significantly reducing the agglomeration of MoS.

Genome-wide survey and characterization of transcription factors in the silk gland of the silkworm, Bombyx mori.

Transcription factors (TFs) are key proteins that modulate gene transcription and thereby lead to changes in the gene expression profile and the subsequent alteration of cellular functions. In the silk gland (SG) of silkworm Bombyx mori, an important silk-producing insect, TFs are of vital importance in the regulation of silk protein synthesis in this organ. However, which TFs exist and express in the SG remains largely unknown.

Urban-rural differences in catastrophic health expenditure among households with chronic non-communicable disease patients: evidence from China family panel studies.

Background: The prevalence of chronic non-communicable diseases (NCDs) challenges the Chinese health system reform. Little is known for the differences in catastrophic health expenditure (CHE) between urban and rural households with NCD patients. This study aims to measure the differences above and quantify the contribution of each variable in explaining the urban-rural differences.

Electrochemical Fixation of Nitrogen by Promoting N Adsorption and N-N Triple Bond Cleavage on the CoS/MoS Nanocomposite.

An electrochemical N reduction reaction (NRR), as an environmentally benign method to produce NH, is a suitable alternative to substitute the energy-intensive Haber-Bosch technology. Unfortunately, to date, it is obstructed by the lack of efficient electrocatalysts. Here, a CoS/MoS nanocomposite with CoS nanoparticles decorated on MoS nanosheets is fabricated and adapted as a catalyst for the NRR.

Klotho Deficiency Causes Heart Aging via Impairing the Nrf2-GR Pathway.

Rationale: Cardiac aging is an important contributing factor for heart failure, which affects a large population but remains poorly understood.

Objective: The purpose of this study is to investigate whether Klotho plays a role in cardiac aging.

Methods And Results: Heart function declined in old mice (24 months), as evidenced by decreases in fractional shortening, ejection fraction, and cardiac output.