The stems of Syringa oblata Lindl. exert cardioprotective effects against acute myocardial ischemia by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome signaling pathways in mice.

Ethnopharmacological Relevance: The stripped roots and stems of Syringa oblata Lindl. (SO), a Mongolian and Tibetan folk medicinal plant, are renowned for their traditional use against "Khii", pain relief, and heat clearing. It is used to treat cardiovascular diseases (CVDs), upset, insomnia, and other symptoms and is commonly used as a substitute for another plant known as S.

Anti-inflammatory lignans from peeled stems of Syringa pinnatifolia.

Three new lignans namely alashanenols H-J (1-3) and one dimeric lignan namely bisyringol A (4) together with 15 known analogues (5-19) were isolated from the peeled stems of Syringa pinnatifolia Hemsl. with the aid of an in vitro anti-inflammation guided fractionation. The structures were elucidated by analysis of spectroscopic data, including IR, UV, MS, and NMR, and their absolute configurations were resolved by X-ray single crystal diffraction analysis and comparison of experimental and calculated C NMR and ECD data.

Hendersines J-M: Isoquinoline alkaloids from Corydalis hendersonii Hemsl. with cardiomyocyte protective and NO production inhibitory effects.

Six isoquinoline alkaloids were identified from the alkaloid-rich fraction of Corydalis hendersonii Hemsl, including five previously undescribed isoquinoline alkaloids hendersines J-M (1a, 1b, and 2-4) and isobicuculline (5), a compound reported for the first time from a natural source. Their structures were elucidated based on spectroscopic analysis of HR-ESI-MS, 1D and 2D NMR, X-ray diffraction, and ECD. Compounds 1a and 1b represent a pair of rare three-nitrogen isoquinoline alkaloid enantiomers, while 2 and 3 are isoquinoline alkaloids featuring a benzo-fused N-heterocycle.