Characteristics of the Deconvolved Transient AEP from 80 Hz Steady-State Responses to Amplitude Modulation Stimulation.

This study aimed to validate the existence and investigate the characteristics of the transient responses from conventional auditory steady-state responses (ASSRs) using deconvolution methods capable of dealing with amplitude modulated (AM) stimulation. Conventional ASSRs to seven stimulus rates were recorded from 17 participants. A deconvolution method was selected and modified to accommodate the AM stimulation.

Auditory Deficits in Patients With Mild and Moderate Obstructive Sleep Apnea Syndrome: A Speech Syllable Evoked Auditory Brainstem Response Study.

Objectives: The energy consumption process of cochlea and neural signal transduction along the auditory pathway are highly dependent on blood oxygen supply. At present, it is under debate on whether the obstructive sleep apnea syndrome (OSAS) would affect the auditory function since the patients suffer from low oxygen saturation. Moreover, it is difficult to detect the functional state of auditory in less severe stage of OSAS.

[Noise attenuation analysis on auditory evoked potential based on maximum length sequence].

The maximum length sequence (m-sequence) has been successfully used to study the linear/nonlinear components of auditory evoked potential (AEP) with rapid stimulation. However, more study is needed to evaluate the effect of the m-sequence order in terms of the noise attenuation performance. This study aimed to address this issue using response-free electroencephalogram (EEG) and EEGs with nonlinear AEPs.

[Progress of generation mechanisms of auditory steady-state response].

The scalp-recorded auditory steady-state response (ASSR) is a periodically evoked potential in response to the stimulation with the acoustical property in the same period. The ASSR can be readily induced in comparison with transient responses for specific conditions. The clinical utility of ASSR may be unjustified for the ambiguity of the genesis.

Improved Transient Response Estimations in Predicting 40 Hz Auditory Steady-State Response Using Deconvolution Methods.

The auditory steady-state response (ASSR) is one of the main approaches in clinic for health screening and frequency-specific hearing assessment. However, its generation mechanism is still of much controversy. In the present study, the linear superposition hypothesis for the generation of ASSRs was investigated by comparing the relationships between the classical 40 Hz ASSR and three synthetic ASSRs obtained from three different templates for transient auditory evoked potential (AEP).

[Effectiveness of cisplatin on the expressions of Bcl-2 and Bax in cochlea and spiral ganglion cells of guinea pigs].

Objective: To investigate the effectiveness of cisplatin on the expressions of Bcl-2 and Bax in cochlea and spiral ganglion cells (SGC) of guinea pigs.

Method: Twenty guinea pigs were randomly divided into cisplatin (n = 10) and control groups (n = 10). Cisplatin group were administrated with a dose of intraperitoneal injection of 16 mg/kg, while the control group were received intraperitoneal injection of normal saline as placebo.

[Relationships of electrophysiological characteristic between speech evoked auditory brainstem response and auditory mismatch negativity].

Objective: To investigate the relationships of electrophysiological characteristics between speech evoked auditory brainstem response (s-ABR) and auditory mismatch negativity (MMN), so as to provide more clues for the mechanism of speech cognitive behavior.

Method: Thirty-three ears in 33 normal hearing adults were included in this study. Their s-ABR were recorded with speech syllables /da/ at 80 dB HL intensity.

[The effectiveness of endoscopic tragus cartilage-perichondrium myringoplasty in the treatment of large tympanic membrane perforations].

Objective: To evaluate effectiveness of endoscopic tragus cartilage-perichondrium in the treatment of large tympanic membrane perforations.

Method: Patients with large tympanic membrane perfortations who had underwent cartilage-perichondrium myringoplasty were retrospectively retrieved from our department. Those with a follow-up of equal to or greater than 12 months after surgery were included in the study.

[Instantaneous energy spectrum analysis for frequency following response of speech evoked brainstem response].

Speech evoked brainstem responses (s-ABRs) elicited by a speech syllable /da/ are composed of four parts: onset response (OR), transitional response, frequency following response (FFR) and offset response. FFR elicited by periodic events behaves like a quasi-periodic waveform corresponding to the stimulus sounds. The fast Fourier transform based spectra are commonly used to exam the characteristics of s-ABR in practice, which is, however, unable to trace the occurrence of the main components of s-ABR.

[Comparison of the efficiency of techniques for deconvolving auditory-evoked potentials with high rate stimulation].

In some auditory evoked potential (AEP) examinations, high rate stimulation paradigms deliver more stimuli with the same period of time, which might lead to overlapping responses. At present, several established techniques can be proposed to address such problem, thus the research scope in both scientific and clinical applications is expanded. In this study, the restoring efficiency of evoked responses is investigated using a simulation strategy.

[Comparison of auditory brainstem responses to speech from bilateral ears with ipsilateral recordings].

Objective: To compare the time domain and the frequency domain of speech-evoked auditory brain-stem response measured by stimulation of left and right ears, and to explore the difference and possible reasons of neural coding for speech from different ears in auditory brainstem.

Method: Speech-ABRs to syllable /da/ of 31 healthy adults were recorded. Statistical analysis was performed on time-domain parameters, such as latencies and amplitudes of featured peaks, and frequency-domain ones, such as amplitudes of the fundamental frequency and the first formant of speech-ABRs ranging from 20-50 ms.

[Components and characteristics of speech-ABR from healthy young adults.].

Objective: To determine the electrophysiological characteristics of speech evoked-ABR, which are then related to the acoustic properties of stimulus sound in terms of the latencies of the main components, and moreover compared to the conventional click-ABR to explore their underlying relationships.

Methods: The speech-ABR and click-ABR were recorded from 31 healthy young adults without any hearing problem examined by audiometric screen processes. The speech syllable/da/was synthesized by Klatt method.