Inhibition of id-1 reduces osteosarcoma growth and metastasis through mediation of snail.

Objective: Osteosarcoma (OS) is a highly invasive bone tumor that frequently metastasizes to the lungs. This study aims to investigate the role of the Id-1 gene in OS invasion and metastasis, and its relationship with the Snail gene.

Methods: This study included tissue samples from 12 non-metastatic osteosarcomas and 9 metastatic osteosarcoma patients to examine the expression of Id-1 and Snail using RT-qPCR and analyze their correlation.

[Application of personalized digital analog assisted acetabular prosthesis precise implantation in Crowe typeⅠand Ⅱ hip dysplasia].

Objective: To explore the effect of personalized digital analog assisted acetabular prosthesis precise implantation in hip dysplasia.

Methods: From February 2017 to July 2019, 11 patients(12 hips) with hip dysplasia underwent total hip arthroplasty, including 4 males(5 hips) and 7 females(7 hips), aged from 27 to 61 years old, with an average of (46.64±12.