Establishment of potential lncRNA-related hub genes involved competitive endogenous RNA in lung adenocarcinoma.

Long non-coding RNAs (lncRNAs) have a notable role in the diagnosis and prognosis of cancer. However, the associations between lncRNA-related hub genes (LRHGs) expression and the corresponding outcomes have not been fully understood in lung adenocarcinoma (LUAD). Here, a total of 71 patients diagnosed with LUAD and 60 healthy volunteers at The First Affiliated Hospital of Huzhou University from April, 2023 to December, 2023 were enrolled in the present study.

Research and Analysis of Molecules such as CD28, CD45RA, CD45RO, CD38, HLA-DR, and CD57 on T Cells in Multiple Myeloma.

Background: For many years it has been postulated that the immune system controls the progress of multiple myeloma (MM). However, the phenotypes of T cells in MM remain to be elucidated. In this study, we compared the phenotypes of T cells, which were obtained from the peripheral blood, in MM patients with those in healthy donors (HD).

The effect of receptive music therapy on older adults with mild cognitive impairment and depression: a randomized controlled trial.

This study aims to evaluate the effects of a receptive music therapy intervention on cognitive functions and depressive symptoms in older adults with MCI. A randomized controlled trial was conducted in Wuhan, China. Eighty older adults, over 65, who had MCI and depression symptoms were randomly divided into the intervention and control groups.

Therapy-related acute myeloid leukemia with in a patient with ovarian cancer after exposure to chemotherapy.

In patients with acute myeloid leukemia (AML), about 25%-35% of patients have a history of other hematological diseases, 10% of patients have a history of malignant tumors in other systems and have received cytotoxic treatment including chemotherapy and/or radiation, and the disease is categorized as therapy-related acute myeloid leukemia (t-AML) according to the World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues. Two subsets of t-AML are generally recognized based on the nature of prior treatments and the characteristics of the disease. The most common type occurs after exposure to alkylating agents and/or radiation, with a latent period of 5 to 10 years.

Foxtail millet [ (L.) P. Beauv.] grown under nitrogen deficiency exhibits a lower folate contents.

Foxtail millet [ (L.) P. Beauv.

Rh(III)-Catalyzed Synthesis of Amino-isocoumarins with -Functionalized Cyclic Carbonates via C-H/O-H Annulation.

A practical method to access amino-isocoumarins catalyzed by a Rh(III) complex through redox-neutral C-H/O-H annulation has been disclosed. The use of -functionalized cyclic carbonates is crucial to facilitate the catalytic turnover, and a broad spectrum of amino-isocoumarin derivatives were prepared with satisfactory yields. Amino-isocoumarin estrone conjugated with a selenocyano functionality was identified to be nearly four times as active as the marketed drug abiraterone against T47D cancer cells.

Efficient Catalytic Combustion of Cyclohexane over PdAg/FeO Catalysts under Low-Temperature Conditions: Establishing the Degradation Mechanism Using PTR-TOF-MS and DRIFTS.

Cyclohexane, a typical volatile organic compound (VOC), poses high risks to the environment and humans. Herein, synthesized PdAg/FeO catalysts exhibited exceptional catalytic performance for cyclohexane combustion at lower temperatures (50% mineralization temperature () of 199 °C, 90% mineralization temperature () of 315 °C) than Pd/FeO ( of 262 °C, of 335 °C) and FeO ( of 305 °C, of 360 °C). In addition, PdAg/FeO displayed enhanced stability by alloying Ag with Pd.

Value of subcarinal lymph node dissection in esophageal cancer surgery: A case-control study.

We investigated the value of subcarinal lymph node dissection in esophageal cancer surgery. Altogether, 240 patients with esophageal cancer admitted to our department between June 2012 and January 2016 were prospectively assigned to an experimental group (subcarinal lymph node dissection group, n = 120 cases) and a control group (uncleaned group, n = 120 cases). The number of subcarinal lymph nodes and the rate of subcarinal lymph node metastasis were determined, and the factors influencing subcarinal lymph node metastasis were analyzed using logistic regression in the experimental group.

Serum Levels of CXCL-13, RBP-4, and IL-6, and Correlation Analysis of Patients with Graves' Disease.

Objective: To investigate the serum levels of CXC chemokine 13 (CXCL-13), retinol binding protein-4 (RBP-4), and interleukin 6 (IL-6) in patients with Graves' disease (GD). The correlation between CXCL-13, RBP-4, and IL-6 levels and the basal metabolic rate (BMR) was analyzed.

Methods: 118 GD patients diagnosed in our hospital were selected as the observation group from March 2017 to December 2018.

Night warming at the vegetative stage improves pre-anthesis photosynthesis and plant productivity involved in grain yield of winter wheat.

We conducted pot experiments during the 2018-2020 growing seasons to study the effects of night warming at different growth stages of wheat on the photosynthetic performance; accumulation, transportation, and distribution of dry matter; and grain yield of winter wheat. Night warming at all the different growth stages resulted in an elevation of wheat yield by increasing the 1000-grain weight and the number of grains per ear. Night warming during the period from jointing to booting stage resulted in the greatest increase in wheat yield.

Clinical Care of Hyperthyroidism Using Wearable Medical Devices in a Medical IoT Scenario.

This paper presents an in-depth study and analysis of clinical care of patients with hyperthyroidism using wearable medical devices in the context of medical IoT scenarios. According to the use scenario of the gateway and the connectivity of the equipment, the hardware architecture, hardware interfaces, functionality, and performance of the gateway were briefly designed, so as to monitor patients with hyperthyroidism more comprehensively and save labor costs. The gateway can provide access to different devices and adaptation functions to different hardware interfaces and provide hardware support for the subsequent deployment of the proposed new medical communication protocols and related information systems.

Design and Implementation of Intelligent Monitoring System for Head and Neck Surgery Care Based on Internet of Things (IoT).

As a chronic disease, cervical spondylosis is prone to recurrent attacks as we age if we do not pay attention to protection, which can easily lead to symptoms such as osteophytes and herniated discs. In the early stage of cervical spondylosis, it is possible to alleviate the disease and prevent its aggravation by improving poor cervical posture and increasing cervical activities. This article analyzes the current situation and medical prospect of smart wearable devices with the prevention and treatment of cervical spondylosis in white-collar people as the starting point and smart wearable devices as the focus and provides a detailed analysis of the functions, categories, technologies, and applications of smart wearable devices to provide a technical theoretical basis for the construction of the subsequent research system.

Both Gut Microbiota and Differentially Expressed Proteins Are Relevant to the Development of Obesity.

Although the role of the gut microbiota in obesity has recently received considerable attention, the exact mechanism is unclear. This study was aimed at investigating the profiles of bacterial communities in fecal samples and differentially expressed proteins (DEPs) in the peripheral blood in mice fed a high-fat diet (HFD) and standard diet (SD) and at providing new insights into the pathogenesis of obesity. The profiles of bacterial communities in fecal samples and DEPs in the peripheral blood were characterized in mice fed HFD and SD, respectively.

Resveratrol Supplementation Prevents Hypertension in Hypertensive Pregnant Rats by Increasing Sodium Excretion and Serum Nitric Oxide Level.

Background: Pregnancy-induced hypertension (PIH) remains a major cause of morbidity and mortality in pregnancy worldwide. This study was designed to study the blood pressure-lowering effect of resveratrol (RES) in a salt-induced hypertensive pregnant rat model.

Methods: Forty female Sprague Dawley (SD) rats were randomized into 4 groups: Normal Preg (0.

Anaplastic lymphoma kinase-negative pulmonary inflammatory myofibroblastic tumor with multiple metastases and its treatment by Apatinib: A case report.

Rationale: Primary pulmonary inflammatory myofibroblastic tumor (IMT) with distant metastasis is extremely rare. Moreover, metastasis of pulmonary IMT to bone marrow has never been reported in previous studies. Therapeutic approaches for anaplastic lymphoma kinase (ALK)-negative pulmonary IMT with metastasis are limited.

Driving forces of impervious surface in a world metropolitan area, Shanghai: threshold and scale effect.

Shanghai is one of the largest metropolitan areas in the world, during the rapid urbanization of the past decades, impervious surface expanded dramatically and became a main factor influencing surface water quality. Thus, exploring the driving forces of impervious surface has great implications in such metropolitan area. In this study, an impervious surface coefficient method (ISC) was used to measure the percentage of total impervious area (PTIA) of Shanghai; regression analysis was conducted to define the relationship between PTIA and three socio-economic factors, population density, unit area gross domestic product, and unit area industrial output at the city and district scale.

Both gut microbiota and cytokines act to atherosclerosis in ApoE-/- mice.

Background: Several studies have suggested a role for the gut microbiome and cytokines in atherosclerosis development, but combined analyses of the changes of the gut microbiota and cytokines have not been explored previously.

Methods: We treated ApoE-/- and wild-type mice with a high-fat diet for 12 weeks. The gut microbiome and cytokine composition were analyzed using 16S ribosomal DNA sequencing and RayBio Quantibody Arrays, respectively.

A system dynamics modelling simulation based on a cohort of hepatitis B epidemic research in east China community.

Hepatitis B constitutes a severe public health challenge in China. The Community-based Collaborative Innovation hepatitis B (CCI-HBV) project is a national epidemiological study of hepatitis B and has been conducting a comprehensive intervention in southern Zhejiang since 2009.The comprehensive intervention in CCI-HBV areas includes the dynamic hepatitis B screening in local residents, the normalised treatment for hepatitis B infections and the upcoming full-aged hepatitis B vaccination.

The diagnosis and management of rare cystic liver metastases from nasopharyngeal carcinoma: A case report.

Rational: Nasopharyngeal carcinoma (NPC) with cystic liver metastases is so rarely observed that there are only three cases reported in the published literature.

Patient Concerns: We present a case of NPC that received complete response after chemotherapy and definitive radiotherapy, but a liver cystic lesion was revealed on abdominal sonogram three months after the initial therapy. The cystic liver lesion initially resembled a simple liver cyst with fast growth, and then evolved into an abscess-like mass after a short term.

Thermodynamic models to elucidate the enantioseparation of drugs with two stereogenic centers by micellar electrokinetic chromatography.

An equilibrium model depicting the simultaneous protonation of chiral drugs and partitioning of protonated ions and neutral molecules into chiral micelles in micellar electrokinetic chromatography (MEKC) has been introduced. It was used for the prediction and elucidation of complex changes in migration order patterns with experimental conditions in the enantioseparation of drugs with two stereogenic centers. Palonosetron hydrochloride (PALO), a weakly basic drug with two stereogenic centers, was selected as a model drug.

Structure and third-order nonlinear optical properties of the two-dimensional Co coordination polymer [Co(1,2-BIB)(PA)] {1,2-BIB is 1,2-bis[(1H-imidazol-1-yl)methyl]benzene and HPA is phthalic acid}.

The design of nonlinear optical (NLO) materials with large NLO responses has been a challenge for materials scientists and chemists. Recently, organic polymers have received attention regarding their NLO properties and fast nonlinear response, and clusters involving delocalized dπ-pπ systems and conjugated dπ-pπ systems are expected to be a new class of NLO materials. Metal-organic coordination polymers combine the advantages of the organic and inorganic species.

Assessing the comprehensive restoration of an urban river: an integrated application of contingent valuation in Shanghai, China.

Around 2000, China began to address the comprehensive restoration of its urban rivers and attempt to restore river ecosystem services. This paper reports an integrated contingent valuation of the ecosystem services of Zhangjiabang Creek in Shanghai, which is in the most developed region of China. A total of 1440 questionnaires were delivered, and 1153 were returned as usable in August 2008.

[Medical exchanges between China and Vietnam during the Song, Jin and Yuan Periods].

There were many medical exchanges between China and Vietnam during the Song, Jin and Yuan Periods. For example, in the Li Period, Vietnam established the Imperial Medical Department according to medical administration in China and to the Chen Period, the name was changed to Imperial Academy of Medicine. Through tribute and trade, many medicines circulated between the two countries.