Publications by authors named "Qiuwen Ye"

Background: Early, non-invasive identification can generally enhance the survival rate for asymptomatic pancreatic cancer (PC). This systematic review and meta-analysis is conducted to evaluate the precision of diagnosing PC using serum and duodenal fluid exosomes.

Methods: Following the guidelines of PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses), searches were conducted in the PubMed, Embase, Cochrane Library, and Web of Science databases in April 2024.

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Article Synopsis
  • Pancreatic adenocarcinoma (PAAD) is a challenging cancer with a low survival rate, and this study focuses on integrin subunit genes (ITGs) as potential prognostic markers for PAAD.
  • The researchers utilized RNA-sequencing data and clinicopathological information to analyze ITG expression in PAAD, identifying 22 key ITGs linked to various cancer pathways.
  • A prognostic model was developed based on these ITGs, revealing differences in immune cell proportions and gene expressions between high and low-risk PAAD groups, which could help in improving patient outcomes.
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Background: Pancreatic cancer is a highly aggressive malignancy with poor prognosis, and there is an urgent need to understand its molecular mechanisms for early diagnosis and treatment. Despite surgical resection being the only effective treatment, most patients are diagnosed at an advanced stage, missing the optimal window for therapy. Identifying novel biomarkers is crucial for prognostic assessment, treatment planning, and early intervention.

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LncRNA maternally expressed gene 3 (MEG3) is a potential prognostic and diagnostic biomarker in colorectal carcinoma (CC). However, its cellular functions and mechanism remain not fully uncovered. Relative expression of MEG3, miRNA (miR)-103a-3p, and pyruvate dehydrogenase E1 subunit beta (PDHB) was detected by RT-qPCR and western blotting.

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ATPase family AAA domain-containing protein 3 () is a mitochondrial membrane-bound ATPase that is involved in a number of cellular processes and is linked with the progression of various types of malignancies. In primates, the gene cluster contains and . The association between gene cluster expression and hepatocellular carcinoma (HCC) remains unknown.

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