Cloning and characterization of the virulence factor Hop from Vibrio splendidus.

Background: Vibrio splendidus is an aquaculture pathogen that can cause skin ulcer syndrome (SUS) in Apostichopus japonicus. HopPmaJ is a type III system effector (T3SE) that has been reported to be an important virulence factor. In this study, a gene named hop, which encodes HopPmaJ in V.

Dihydrolipoamide dehydrogenase of is involved in adhesion to .

is one of the most opportunistic marine pathogens and infects many important marine animals, including the sea cucumber . In this study, two genes named and , encoding dihydrolipoamide dehydrogenase (DLD) homologues in pathogenic , were cloned, and conditionally expressed in BL21 (DE3). The enzymatic activities of DLD1 and DLD2 showed that they both belonged to the NADH oxidase family.

Outer membrane protein OmpU is related to iron balance in Vibrio alginolyticus.

Outer membrane protein U (OmpU) is a major porin from Vibrio alginolyticus and has been considered a vaccine candidate against infection by V. alginolyticus. After pre-incubated with polyclonal antibody against rOmpU, V.