Alterations in the Fecal Microbiota Composition in Pediatric Acute Diarrhea: A Cross-Sectional and Comparative Study of Viral and Bacterial Enteritis.

Objective: To examine the association between the fecal microbiota of acute diarrhea in children and provide gut microbiota information related the acute diarrhea with rotavirus.

Patients And Methods: Children with acute diarrhea aged 3-60 months were selected for the study. Routine stool examination was performed, and stool samples were collected and stored at -80 °C until further analysis.

Mutations in the Antibiotic Target Genes Related to Clarithromycin, Metronidazole and Levofloxacin Resistance in Strains from Children in China.

Purpose: This study aimed to characterize common mutations of antibiotic-resistant gene of clarithromycin, metronidazole and levofloxacin in () and determine their association with antibiotic resistance of for providing a strategy for eradication therapy of infection in children.

Patients And Methods: The antibiotic resistance to clarithromycin, metronidazole and levofloxacin for strains isolated from children was determined by E-test. The mutation of domain V of 23S rRNA, and and genes was performed by PCR-based sequencing of DNA fragments.