High temperature heat flux sensor with ITO/InO thermopile for extreme environment sensing.

Hypersonic vehicles and aircraft engine blades face complex and harsh environments such as high heat flow density and high temperature, and they are generally narrow curved spaces, making it impossible to actually install them for testing. Thin-film heat flux sensors (HFSs) have the advantages of small size, fast response, and in-situ fabrication, but they are prone to reach thermal equilibrium and thus fail during testing. In our manuscript, an ITO-InO thick film heat flux sensor (HFS) is designed, and a high-temperature heat flux test system is built to simulate the working condition of a blade subjected to heat flow impact.

Laser-upgraded coal tar for smart pavements in road and bridge monitoring applications.

The implementation of an intelligent road network system requires many sensors for acquiring data from roads, bridges, and vehicles, thereby enabling comprehensive monitoring and regulation of road networks. Given this large number of required sensors, the sensors must be cost-effective, dependable, and environmentally friendly. Here, we show a laser upgrading strategy for coal tar, a low-value byproduct of coal distillation, to manufacture flexible strain-gauge sensors with maximum gauge factors of 15.

Synergistic advancements in high-performance flexible capacitive pressure sensors: structural modifications, AI integration, and diverse applications.

The development of flexible pressure sensors for monitoring human motion and physiological signals has attracted extensive scientific research. However, achieving low monitoring limits, a wide detection range, large bending stresses, and excellent mechanical stability simultaneously remains a serious challenge. With the aim of developing a high-performance capacitive pressure sensor (CPS), this paper introduces the successful preparation of a single-walled carbon nanotube (SWNT)/polydimethylsiloxane (S-PDMS) composite dielectric with a foam-like structure (high permittivity and low elasticity modulus) and MXene/SWNT (S-MXene) composite film electrodes with a micro-crumpled structure.

TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.

Background: Tandem C2 domains, nuclear (TC2N) is a C2 domain-containing protein that belongs to the carboxyl-terminal type (C-type) tandem C2 protein family, and acts as an oncogenic driver in several cancers. Previously, we preliminarily reported that TC2N mediates the PI3K-Akt signaling pathway to inhibit tumor growth of breast cancer (BC) cells. Beyond that, its precise biological functions and detailed molecular mechanisms in BC development and progression are not fully understood.

Temperature, pressure, and humidity SAW sensor based on coplanar integrated LGS.

This paper presents a surface acoustic wave (SAW) sensor based on coplanar integrated Langasite (LGS) that is fabricated using wet etching, high-temperature bonding, and ion beam etching (IBE) processes. The miniaturized multiparameter temperature‒pressure-humidity (TPH) sensor used the MXene@MoS@Go (MMG) composite to widen the humidity detection range and improve the humidity sensitivity, including a fast response time (3.18 s) and recovery time (0.

Printing Three-Dimensional Refractory Metal Patterns in Ambient Air: Toward High Temperature Sensors.

Refractory metals offer exceptional benefits for high temperature electronics including high-temperature resistance, corrosion resistance and excellent mechanical strength, while their high melting temperature and poor processibility poses challenges to manufacturing. Here this work reports a direct ink writing and tar-mediated laser sintering (DIW-TMLS) technique to fabricate three-dimensional (3D) refractory metal devices for high temperature applications. Metallic inks with high viscosity and enhanced light absorbance are designed by utilizing coal tar as binder.

A wireless demodulation system based on a multi-parameter resonant sensor.

This paper proposes a wireless passive measurement system that supports real-time signal acquisition, multi-parameter crosstalk demodulation, and real-time storage and calculation. The system consists of a multi-parameter integrated sensor, an RF signal acquisition and demodulation circuit, and a multi-functional host computer software. The sensor signal acquisition circuit uses a wide frequency detection range (25 MHz-2.

Long-term exposure to low levels of okadaic acid accelerates cell cycle progression in colonic epithelial cells via p53 and Jak/Stat3 signaling pathways.

As a major component of diarrheic shellfish poisoning (DSP) toxins, okadaic acid (OA) is widely distributed worldwide, and causes a series of serious public health problems. In colon tissue, previous studies have shown that high doses of OA can affect various intracellular processes, including destroy intercellular communication at gap junctions, induce cell apoptosis and trigger cell cycle arrest. However, there is a scarcity of studies on the effect and mechanism of action of low doses of OA in colonic tissues.

Novel Surface Acoustic Wave Temperature-Strain Sensor Based on LiNbO for Structural Health Monitoring.

In this paper, we present the design of an integrated temperature and strain dual-parameter sensor based on surface acoustic waves (SAWs). First, the COMSOL Multiphysics simulation software is used to determine separate frequencies for multiple sensors to avoid interference from their frequency offsets caused by external physical quantity changes. The sensor consists of two parts, a temperature-sensitive unit and strain-sensitive unit, with frequencies of 94.

Simulation Design of Surface Acoustic Wave Sensor Based on Langasite Coplanar Integration with Multiple Parameters.

In the harsh environment of high temperature and high rotation, a single parameter is difficult to satisfy the multi-parameter test requirements of aerospace metallurgy. Therefore, a multi-parameter coplanar integrated surface acoustic wave (SAW) sensor based on Langasite (LGS) is proposed. In this paper, the optimal cut for different measurement parameters is analyzed, and the optimal cut to temperature, pressure and vibration are obtained.

Langasite Bonding via High Temperature for Fabricating Sealed Microcavity of Pressure Sensors.

We proposed a novel Langasite (LGS) bonding method only using high temperature to solve the manufacturing difficulty of the sealed microcavity of pressure sensors. The optimal bonding parameters by comparative experiments were defined as 1350 °C for 3 h. Due to simple experimental conditions, low experimental cost, and be suitable for bonding wafers with various sizes, the method is convenient for popularization and mass-production, thus promoting the development of surface acoustic wave (SAW) devices at high temperatures.

Voltage standing wave ratio reading circuit design for inductance capacitance wireless passive ammonia sensors.

It is not easy to conduct wired tests on sensors in harsh environments, and network analyzers are large, heavy, and inconvenient to carry. At the same time, the price of network analyzers is usually very high, which greatly limits their application. In this study, a voltage standing wave ratio reading circuit is designed to test inductively coupled (LC) wireless passive sensors.

Novel Multilayer SAW Temperature Sensor for Ultra-High Temperature Environments.

Performing high-temperature measurements on the rotating parts of aero-engine systems requires wireless passive sensors. Surface acoustic wave (SAW) sensors can measure high temperatures wirelessly, making them ideal for extreme situations where wired sensors are not applicable. This study reports a new SAW temperature sensor based on a langasite (LGS) substrate that can perform measurements in environments with temperatures as high as 1300 °C.

Stereotactic Body Radiotherapy Is Effective in Modifying the Tumor Genome and Tumor Immune Microenvironment in Non-Small Cell Lung Cancer or Lung Metastatic Carcinoma.

Background And Purpose: To directly reveal the change in genome mutation, RNA transcript of tumor cells, and tumor microenvironment (TME) after stereotactic body radiotherapy (SBRT) in paired human lung tumor specimens.

Materials And Methods: Paired tumor samples were collected from 10 patients with non-small cell lung cancer (NSCLC) or lung metastatic carcinoma within a week before and after SBRT. DNA and RNA of tumor tissues was extracted from the paired samples.

Wireless Passive LC Temperature and Strain Dual-Parameter Sensor.

There is an increasing demand for bearing temperature and strain monitoring in high-speed rotating systems. This study proposes a new multiresonance, multiplexing, wireless, passive inductance capacitance (LC) temperature and strain sensor. The sensor has two capacitors connected at different locations (turns) on the same inductor to achieve simultaneous temperature and strain measurements.

Increased DEF6 expression is correlated with metastasis and poor prognosis in human osteosarcoma.

Metastasis is the primary cause of high mortality in patients with osteosarcoma (OS). However, the molecular mechanisms underlying the regulation of metastatic disease are yet to be determined. Differentially expressed in FDCP 6 homolog (DEF6) has been demonstrated to be correlated with the metastatic behavior of several cancers, such as breast, ovarian and colorectal cancers.

Highly Sensitive NH Wireless Sensor Based on Ag-RGO Composite Operated at Room-temperature.

The detection of ammonia (NH) in low concentrations is very important in the chemical industry and for human health. In this paper, we present reduced graphene oxide (RGO) decorated with silver nanoparticles (AgNPs) as a sensing material for NH. A simple, environmentally friendly, and cost-efficient green approach for the preparation of the sensing material is proposed.

High expression of ID1 facilitates metastasis in human osteosarcoma by regulating the sensitivity of anoikis via PI3K/AKT depended suppression of the intrinsic apoptotic signaling pathway.

A lack of understanding of the molecular basis underlying the regulation of metastatic disease and its effective therapy are the primary causes of high mortality in osteosarcoma. Thus, new insights into metastases and novel effective targets for metastatic osteosarcoma are urgently required. Anoikis resistance is considered a hallmark of cancer cells with metastatic ability.

Wireless wide-range pressure sensor based on graphene/PDMS sponge for tactile monitoring.

We propose a flexible wireless pressure sensor, which uses a graphene/polydimethylsiloxane (GR/PDMS) sponge as the dielectric layer. The sponge is sandwiched between two surfaces of a folded flexible printed circuit with patterned Cu as the antenna and electrode. By adjusting graphene and NHHCO concentrations, a composite with 20% concentration of NHHCO and 2% concentration of graphene as the dielectric layer is obtained, which exhibits high sensitivity (2.

Al₂O₃-Based a-IGZO Schottky Diodes for Temperature Sensing.

High-temperature electronic devices and sensors that operate in harsh environments, especially high-temperature environments, have attracted widespread attention. An Al₂O₃ based a-IGZO (amorphous indium-gallium-zinc-oxide) Schottky diode sensor is proposed. The diodes are tested at 21⁻400 °C, and the design and fabrication process of the Schottky diodes and the testing methods are introduced.

A MoS₂ Nanoflakes-Based LC Wireless Passive Humidity Sensor.

In this study, an LC wireless passive humidity sensor based on MoS₂ nanoflakes was proposed. The LC wireless passive humidity sensor was optimized by performing HFSS simulations and fabricated via a screen-printing technique. The MoS₂ nanoflakes were characterized by laser scanning confocal microcopy, scanning electron microscope, and X-ray diffraction.

A Room-Temperature CNT/Fe₃O₄ Based Passive Wireless Gas Sensor.

A carbon nanotube/Fe₃O₄ thin film-based wireless passive gas sensor with better performance is proposed. The sensitive test mechanism of LC (Inductance and capacitance resonant) wireless sensors is analyzed and the reason for choosing Fe₃O₄ as a gas sensing material is explained. The design and fabrication process of the sensor and the testing method are introduced.