Experience Sharing in Pathological Diagnosis of Early Adenocarcinoma of the Lung.

In daily work, there are still many pathologists who have difficulty handling the diagnosis of atypical adenomatous hyperplasia, adenocarcinoma in situ, minimally invasive adenocarcinoma, and lepidic adenocarcinoma, and the boundaries are not clear enough. Sometimes, the diagnosis is difficult, and there is sometimes poor reproducibility between different pathologists. Accurate diagnosis and differential diagnosis require a certain amount of experience.

SERPINE1 and SERPINB7 as potential biomarkers for intravenous vitamin C treatment in non-small-cell lung cancer.

High dose intravenous vitamin C (IVC) has been proposed as a pro-oxidant anticancer agent. However, there is a lack of biomarkers that are specific for this treatment. Here, we explored profiles of gene expression responding to IVC treatment in non-small cell lung cancer (NSCLC) cells as an effort for potential biomarker discovery.

Insight into the Molecular Mechanism of Flower Color Regulation in Franch: A Multi-Omics Approach.

Franch. () is a valuable woody plant known for its high ornamental value. While purple flowers are a distinct and attractive variant phenotype of , the underlying mechanism regulating its flower color is still poorly understood.

Effects of landscape conservation on the ecohydrological and water quality functions and services and their driving factors.

Since the implementation of landscape conservation of the green heart area in the Changsha-Zhuzhou-Xiangtan Metropolitan Region, the landscape structure and pattern have changed significantly. The ecosystem service functions in the area have been improved, but the status of ecohydrological and water quality and service functions (EHWQSFs) is still unclear. To clarify the status of EHWQSFs and their driving factors influenced by landscape conservation, this study analysed landscape changes using remote sensing image data from 1998, 2008, and 2018 and the changes and their spatial characteristics using the Soil and Water Assessment Tool (SWAT) and spatial analysis methods.

Traumatic breast transposal to the abdominal wall: A case report.

Although abdominal wall masses are commonly observed in clinical practice, traumatic breast transposal appearing as an abdominal wall mass is a rare event. The unique phenomenon of a post-traumatic breast growing healthily in the abdominal wall has never previously been reported. The current study presents the case of a 40-year-old female who developed an unusually transposed, but healthy mammary gland in the right upper abdominal wall following a severe pedestrian traffic accident.

Malignant transformation of craniopharyngioma with detailed follow-up.

A 29-year-old male patient was admitted into hospital with the main complaint of progressive visual disturbance. Both CT SCAN and MRI demonstrated a cystic-solid contrast-enhancing sellar-suprasellar mass with obvious calcification. Histopathological examination of the first resected specimen showed a typical appearance of adamantinomatous craniopharyngioma.

[Pulmonary epithelioid hemangioendothelioma: a clinicopathological analysis].

Objective: To report 3 cases of pulmonary epithelioid haemangioendothelioma (PEH) and therefore to improve the understanding of this tumor.

Methods: The clinical pathological features of 3 cases of PEH were described and related literatures were reviewed.

Results: The etiology of this rare disease remained unknown.

[Pleuropulmonary blastoma of adults: a clinicopathological analysis].

Objective: To report two cases of pleuropulmonary blastoma (PPB) of adults and improving the understanding of this tumor.

Methods: The clinicopathological features of two cases of adult PPB were examined by light microscope and an immunohistochemical study.

Results: As a rare malignant mesenchymal tumor, PPB arose from primitive cells of lung, pleura and mediastinum.

Serum proteome analysis for profiling protein markers associated with carcinogenesis and lymph node metastasis in nasopharyngeal carcinoma.

Nasopharyngeal carcinoma (NPC), one of the most common cancers in population with Chinese or Asian progeny, poses a serious health problem for southern China. It is unfortunate that most NPC victims have had lymph node metastasis (LNM) when first diagnosed. We believe that the 2D based serum proteome analysis can be useful in discovering new biomarkers that may aid in the diagnosis and therapy of NPC patients.

[Comparative proteomics of the serum in patients with nasopharyngeal carcinoma: a study with two-dimensional electrophoresis and MALDI-TOF-MS].

Objective: To screen the tumor specific antigens of nasopharyngeal carcinoma (NPC) in the serum of the patients.

Methods: Two-dimensional electrophoresis (2-DE) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) was employed to screen the specific biomarkers of NPC in the sera from 42 healthy volunteers, 37 NPC patients with lymph node metastasis and 27 NPC patients without lymphatic metastasis.

Results: After pretreatment including albumin and immunoglobulin (IgG) depletion and desalting, the sera were subjected to 2-DE and image analysis.

[Comparison of TPS, CEA, CYFRA21-1 and STNFR in diagnosis of lung cancer].

Background: In recent years, new progress has been made in research of tumor markers. And namely tissue polypeptide specific antigen (TPS), cytokeratin 19-fragments (CYFRA21-1) and soluble tumor necrosis factor receptor (STNFR) are new tumor markers that have been used in clinical application. The aim of this study is to determine and compare the diagnostic value of 4 kinds of tumor markers, TPS, carcinoembryonic antigen (CEA), CYFRA21-1 and STNFR in patients with lung cancer.

[Clinical and pathologic features of malignant myoepithelioma of salivary glands].

Objective: To analyze the clinical features, morphology and biologic behavior of primary malignant myoepithelioma (MME) of salivary glands.

Methods: The H&E sections of 16 MME cases were reviewed. Immunohistochemical study using EnVision method for cytokeratin (CK), epithelial membrane antigen (EMA), vimentin, S-100 protein, desmin, muscle-specific actin (MSA), smooth muscle actin (SMA), Myo, proliferation cell nuclear antigen (PCNA), leukocyte common antigen (LCA) and glial fibrillary acidic protein (GFAP) was carried out.