Impact of Maternal BPA Exposure during Pregnancy on Obesity in Male Offspring: A Mechanistic Mouse Study of Adipose-Derived Exosomal miRNA.

Background: The widespread use of bisphenol A (BPA) has led to universal exposure among the population, raising concerns about its health effects. Epidemiological studies have linked environmentally relevant levels of BPA exposure to obesity.

Objectives: We aimed to uncover the complex mechanisms by which oral exposure during pregnancy with BPA affects the offspring.

Elucidating the Molecular Mechanisms and Comprehensive Effects of Sludge-Derived Plant Biostimulants on Crop Growth: Insights from Metabolomic Analysis.

The utilization of urban waste for land management plays a crucial role in reshaping material flows between human activities and the environment. Sewage sludge alkaline thermal hydrolysis (ATH) produces sludge-derived plant biostimulants (SPB), which have garnered attention due to the presence of indole-3-acetic acid. However, there remains a gap in understanding SPB's molecular-level effects and its comprehensive impact on crops throughout their growth cycle.

Tissue accumulation of microplastics and potential health risks in human.

Microplastics have become ubiquitous throughout the environment. Humans constantly ingest and inhale microplastics, increasing concerns about the health risks of microplastic exposure. However, limited data impedes a full understanding of the internal exposure to microplastics.

Relationships between environmental factors and N-cycling microbes reveal the indirect effect of further eutrophication on denitrification and DNRA in shallow lakes.

Traditional views indicate that eutrophication and subsequent algal blooms favor denitrification and dissimilatory nitrate reduction to ammonium (DNRA) in lake ecosystems. However, lakes tend to show an increasing propensity for inorganic nitrogen (N) limitation as they become more eutrophic. Thus, the influence of further eutrophication on denitrification and DNRA in eutrophic lakes are unclear due to the uncertainty of N availability.

Simultaneous antibiotic removal and mitigation of resistance induction by manganese bio-oxidation process.

Microbial degradation to remove residual antibiotics in wastewater is of growing interest. However, biological treatment of antibiotics may cause resistance dissemination by mutations and horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs). In this study, a Mn(Ⅱ)-oxidizing bacterium (MnOB), Pseudomonas aeruginosa MQ2, simultaneously degraded antibiotics, decreased HGT, and mitigated antibiotic resistance mutation.

[Distribution Characteristics and Risk Assessment of PPCPs in Surface Water and Sediments of Lakes in the Lower Reaches of the Huaihe River].

In order to understand the occurrence characteristics and ecological risks of pharmaceuticals and personal care products (PPCPs) in surface water and sediments of Hongze Lake and Gaoyou Lake in the lower reaches of the Huaihe River, 43 surface water and sediment samples from 23 sampling sites were collected, and 61 PPCPs were detected in the samples. The concentration level and spatial distribution of target PPCPs in Hongze Lake and Gaoyou Lake were analyzed, the distribution coefficient of typical PPCPs in the water/sediment system in the study area was calculated, and the ecological risk of target PPCPs was evaluated using the entropy method. The results showed that the PPCPs in surface water of Hongze Lake and Gaoyou Lake were 1.

Microplastics transferring from abiotic to biotic in aquatic ecosystem: A mini review.

Microplastics have been detected in global aquatic ecosystems, so it is vital to understand the bioaccumulation and biomagnification of microplastics for ecological risk assessment. However, variability between studies, including sampling, pretreatment processes, and polymer identification methods have made it difficult to draw definitive conclusions. Alternatively, the compilation and statistical analysis of available experimental and investigation data provides insight into the fates of microplastics in an aquatic ecosystem.

In vivo effects of low dose prenatal bisphenol A exposure on adiposity in male and female ICR offspring.

Background: Bisphenol A (BPA) is known to exhibit endocrine disrupting activities and is associated with adiposity. We examined the obesogenic effect of prenatal BPA exposure in the present study.

Methods: Pregnant ICR mice were exposed to vehicle or BPA via the drinking water at a dose of 0.

Air pollution exposure and the risk of macrosomia: Identifying specific susceptible months.

Birth weight is an important indicator of future growth and development for newborns. Few studies investigated the potential effects of air pollutants on macrosomia and their susceptible windows. We included 38,971 singleton full-term births from Beijing HaiDian Maternal and Child Health Hospital between 2014 and 2018, and assessed the associations of air pollutants exposure during preconception and pregnancy with macrosomia as well as the corresponding susceptible windows.

Water quality criteria and ecological risk assessment for copper in Liaodong Bay, China.

The establishment of water quality criteria (WQC) for copper (Cu) was used as the basis for an ecological risk assessment of marine Cu pollution in Liaodong Bay, China. Published ecotoxicity data for Cu were obtained and supplemented with the results of acute Cu toxicity tests. The marine WQC for Cu in Liaodong Bay was developed using a species sensitivity distribution method with a safety factor of 2.

Identification of microplastics in human placenta using laser direct infrared spectroscopy.

Microplastics are ubiquitous in the environment, including in food and drinking water. Consequently, there is growing concern about the human health risks associated with microplastic exposure through diet. However, the occurrence of microplastics in the human body, particularly in mothers and fetuses, is incompletely understood because of the limited amount of data on their presence in the body and the human placenta.

Ozone exposure induced risk of gestational diabetes mellitus.

Numerous studies have shown that air pollution seems to be able to cause many diseases. Considering the possible mechanism of action and the same growth trend, the present study is designed to examine whether and how air pollutants, especially ozone (O) exposure, are associated with the incidence of gestational diabetes mellitus (GDM). By a retrospective cohort, we analyzed the records of 45439 pregnant women from 2013 to 2018 and matched them to maternal exposure to O.

Acute effects of exposure to fine particulate matter and ozone on lung function, inflammation and oxidative stress in healthy adults.

Both fine particulate matter (PM) and ozone (O) may have adverse effects on human health. However, previous studies on the effects of air pollutants mainly have focused on susceptible population, and evidence on healthy young adults is limited. We aimed to examine the associations of the two main air pollutants (PM and O) with lung function, inflammation and oxidative stress in healthy young adults.

A Carotenoid- and Nuclease-Producing Bacterium Can Mitigate Transformation by Antibiotic Resistance Genes.

Dissemination of antibiotic resistance genes (ARGs) through natural transformation is facilitated by factors that stabilize extracellular DNA (eDNA) and that induce reactive oxygen species (ROS) that permeabilize receptor cells and upregulate transformation competence genes. In this study, we demonstrate that can mitigate this ARG dissemination pathway by removing both eDNA and ROS that make recipient cells more vulnerable to transformation. We used plasmid RP4 as source of extracellular ARGs (, , and ) and the opportunistic pathogen as receptor.

Microfiber releasing into urban rivers from face masks during COVID-19.

Face masks play a crucial protective role in preventing the spread of coronavirus disease during the COVID-19 pandemic, but the improper disposal of used face masks also causes an emerging environmental problem, such as microplastic contamination. Here, the aim was to evaluate the improper disposal of used face masks and, subsequently, the potential contribution to microplastic contamination in urban rivers. First, we investigated the occurrence of discarded face masks in Qing River through continuously one-month collection on-site, and the disposable masks with a density of (8.

Association between per- and polyfluoroalkyl substances and risk of gestational diabetes mellitus.

Background: Existing evidence suggests that perfluoroalkyl and polyfluoroalkyl substances (PFASs) exposure might contribute to the incidence of gestational diabetes mellitus (GDM). This study aimed to perform a meta-analysis to identify the association between PFAS and the risk of GDM.

Methods: We systematically searched PubMed, Ovid, Cochrane Library, and Web of Science databases for appropriate articles about the association between PFASs exposure and the risk of GDM before September 28, 2020.

[Natural Water Chemistry Change in the Surface Water of Chengdu and Impact Factors].

To investigate the impact of megacities on the chemistry of surface waters, monthly sampling and monitoring were conducted in the Chengdu section of the Minjiang and Tuojiang River basin, corresponding to the upper reaches of the Yangtze River since the spring of 2019, including the influent and effluent water samples from 57 sewage treatment plants in Chengdu. All the samples were analyzed for major ions and other water chemistry parameters, and compared with the historical data of the Minjiang and Tuojiang River. The results showed that the Chengdu surface water still presented a natural chemistry with medium-low total dissolved solids(TDS), and calcium bicarbonate chemistry type, which is the natural consequence of the weathering of carbonate rocks in the basin effected by the weathering of silicates and evaporites.

Microplastic characteristics in organisms of different trophic levels from Liaohe Estuary, China.

Microplastics are a growing concern globally due to their small size and easy ingestion by terrestrial and aquatic organisms, resulting in potential adverse impacts on wildlife. However, current data regarding microplastics in wild organisms in different trophic levels is limited. This study investigated microplastic characteristics, including their abundance, size, shape and polymer type, in estuarine invertebrates and vertebrates.

The bacterial community composition and its environmental drivers in the rivers around eutrophic Chaohu Lake, China.

Background: Bacterial community play a key role in environmental and ecological processes in river ecosystems. Rivers are used as receiving body for treated and untreated urban wastewaters that brings high loads of sewage and excrement bacteria. However, little is known about the bacterial community structure and functional files in the rivers around the eutrophic Chaohu Lake, the fifth largest freshwater lake in China, has been subjected to severe eutrophication and cyanobacterial blooms over the past few decades.

Urinary polycyclic aromatic hydrocarbons and sex hormones in children and adolescents: Evidence from NHANES.

Background: Evidences showed that polycyclic aromatic hydrocarbons (PAHs) do harm to human body. However, the association between PAHs and sex hormones in children and adolescents remains unclear.

Objectives: The study aims to investigate the associations between PAHs and sex hormones in the general children and adolescent population.