Risk Factor Analysis and Prediction of Para-Aortic Lymph Node Metastases in Locally Advanced Cervical Cancer.

Background And Purpose: The indications of prophylactic extended-field radiotherapy (EFRT) remain uncertain. This study aims to identify the risk factors for para-aortic lymph node (PALN) metastases in locally advanced cervical cancer (LACC) and determine which part of patients may benefit from prophylactic EFRT.

Materials And Methods: Between January 2015 and July 2023, a single-center retrospective analysis was performed on patients with stages IB3 and IIA2-IVA cervical cancer.

Rhodaelectro-Catalyzed Synthesis of Pyrano[3,4-]indol-1(9)-ones via the Double Dehydrogenative Heck Reaction between Indole-2-carboxylic Acids and Alkenes.

A rhodaelectro-catalyzed double dehydrogenative Heck reaction of indole-2-carboxylic acids with alkenes has been developed for the synthesis of pyrano[3,4-]indol-1(9)-ones. The weakly coordinating carboxyl group is utilized twice as a directing group to activate the C-H bonds throughout the reaction. This reaction precedes an acceptorless dehydrogenation under exogenous oxidant-free conditions in an undivided cell with a constant current.

Non-Noble-Metal-Based Electrocatalysts for Acidic Oxygen Evolution Reaction: Recent Progress, Challenges, and Perspectives.

The oxygen evolution reaction (OER) plays a pivotal role in diverse renewable energy storage and conversion technologies, including water electrolysis, electrochemical CO reduction, nitrogen fixation, and metal-air batteries. Among various water electrolysis techniques, proton exchange membrane (PEM)-based water electrolysis devices offer numerous advantages, including high current densities, exceptional chemical stability, excellent proton conductivity, and high-purity H. Nevertheless, the prohibitive cost associated with Ir/Ru-based OER electrocatalysts poses a significant barrier to the broad-scale application of PEM-based water splitting.

Discovery of Loureirin analogues with colorectal cancer suppressive activity via regulating cell cycle and Fas death receptor.

Chalcones and dihydrochalcones (DHCs) are important bioactive natural products (BNPs) isolated from traditional Chinese medicine. In this study, 13 chalcones were designed with the inspiration of Loureirin, a DHC extracted from Resina Draconis, and synthesized by classical Claisen-Schmidt reactions. Afterwards the reduction reactions were carried out to obtain the corresponding DHCs.

Diversity-Oriented Synthesis of Indole-Fused Polycyclic Scaffolds via Rhodium-Catalyzed -Indole-Directed C-H Coupling of 2-Phenyl-1-indoles with Propargylic Alcohol Derivatives.

Diversity-oriented synthesis strategy for the efficient assembly of indole-fused polycyclic scaffolds via rhodium-catalyzed -indole-directed C-H coupling with propargylic alcohol derivatives in a regioselective manner was developed. Five 2-phenyl-1-indole-embedded core skeletons were synthesized. In particular, three different indole-fused exo-olefin-containing polycycles were realized, which may be manipulated for further chemistry.

Cascade Electrochemical Aerobic Oxygenation of 2-Substituted Indoles and Electrochemical [5 + 3] Annulation with Amidines: Access to Eight-Membered Benzo[1,3,5]triazocin-6(5)-ones.

The cascade electrochemical C3-selective aerobic oxygenation of 2-substituted indoles and electrochemical [5 + 3] annulation with amidines through an undivided cell galvanostatic method employing molecular oxygen and "electricity" as green oxidants was developed. This protocol provides an efficient and direct approach to eight-membered benzo[1,3,5]triazocin-6(5)-ones. Mechanistic studies suggested that two subsequent electrochemical processes both proceeded through radical pathways.

Primary versus secondary cutaneous endometriosis: Literature review and case study.

Cutaneous endometriosis, characterized by the presence of endometrium or endometrial-like tissue outside of the uterine cavity, is an uncommon and chronic disease. Depending on a patient's history, cutaneous endometriosis is classified as either primary cutaneous endometriosis (PCE) or secondary cutaneous endometriosis (SCE). We report a case of SCE presenting with the classic triad of previous caesarean section, subcutaneous nodules at the site of the scar, and pain associated with menstruation.

Rhodaelectro-Catalyzed Decarboxylative Cross-Dehydrogenative Coupling of Indole-3-carboxylic Acids and Olefins via Weakly Coordinating Carboxyl Groups.

A rhodaelectro-catalyzed C2-H selectively decarboxylative alkenylation of 3-carboxy-1-indoles employing electricity as the traceless terminal oxidant has been accomplished. The weakly coordinating carboxyl group serves as the traceless directing groups. External oxidant-free in an undivided cell with constant current in aqueous solution ensures the decarboxylative C-H alkenylation to be viable and sustainable.

Elaborate tree-like Cu-Ag clusters from green electrodeposition for efficiently electrocatalyzing CO conversion into syngas.

The electrocatalytic carbon dioxide reduction (CORR) is one of the emerging technologies that can effectively transform carbon dioxide (CO) into valuable products. Electrocatalysts deriving from green synthesis methods will significantly help to establish a new green carbon cycle. Herein, a green electrodeposition method without additional reducing agents was used to synthesize Cu-Ag bimetallic catalysts, and it is shown that the combination of Cu and Ag obviously affects the morphology of the Cu-Ag catalysts, resulting in the formation of elaborate tree-like Cu-Ag clusters.

Blue-Light Driven Iron-Catalyzed Oxy-phosphinylation of Activated Alkenes for β-Ketophosphine Oxide Synthesis.

We have developed an original blue-light mediated iron-catalyzed oxy-phosphinylation of activated alkenes by secondary phosphine oxides under air at room temperature. Various β-ketophosphine oxides were then obtained in 43-97 % isolated yields. Control experiments revealed that radical process is involved in the mechanism.

Effect of the age of onset on epidemiology, clinical features, and comorbidity of geriatric psoriasis.

Psoriasis is an immune-mediated chronic, relapsing, inflammatory, systemic disease induced by a combination of genetics and environment. Currently, there are limited reports on the epidemiological and clinical characteristics of geriatric psoriatic patients in mainland China. This study analyzed the epidemiological characteristics, clinical features, and comorbidity rates of geriatric patients with psoriasis and evaluated the influence of age of onset on disease characteristics.

Bowl-Assisted Ball Assembly for Solvent-Processing the C Electron Transport Layer of High-Performance Inverted Perovskite Solar Cell.

Pristine fullerene C is an excellent electron transport material for state-of-the-art inverted structure perovskite solar cells (PSCs), but its low solubility leaves thermal evaporation as the only method for depositing it into a high-quality electron transport layer (ETL). To address this problem, we herein introduce a highly soluble bowl-shaped additive, corannulene, to assist in C -assembly into a smooth and compact film through the favorable bowl-ball interaction. Our results show that not only corannulene can dramatically enhance the film formability of C , it also plays a critical role in forming C -corannulene (CC) supramolecular species and in boosting intermolecular electron transport dynamics in the ETL.

The Interactive Effect of Stressor Appraisals and Personal Traits on Employees' Procrastination Behavior: The Conservation of Resources Perspective.

Purpose: Procrastination has become a pervasive phenomenon in the workplace, yet knowledge of its antecedents remains limited. Therefore, this study explains when and why employees procrastinate. As procrastination is an individual intentional behavior to escape potential resource loss by taking actions to relax; this study regards procrastination as resource-protection behavior.

When Is Authoritarian Leadership Less Detrimental? The Role of Leader Capability.

We developed and tested a moderated mediation model of the relationship between authoritarian leadership and employees' task performance as well as their affective organizational commitment. Analyses of multilevel, multisource, and three-wave data from 99 supervisors and 341 subordinates showed that leader effectiveness evaluations mediated the time-lagged relationship of authoritarian leadership with employees' task performance and affective organizational commitment. Moreover, when leader capability is high, it mitigates the negative relationship between AL and employees' outcomes.

Chondroid syringoma of the lower back simulating lipoma: A case report.

Background: Chondroid syringoma (CS) is a rare tumor of the apocrine or eccrine glands. CS of the lower back is rare, and its clinical manifestations are similar to those of lipoma, which is a common misdiagnosis for this disease.

Case Summary: A 39-year-old woman presented with a 2-year history of an asymptomatic subcutaneous mass on the lower back.

Chemodivergent Synthesis of Indeno[1,2-]indoles and Isoindolo[2,1-]indoles via Mn(III)-Mediated or Electrochemical Intramolecular Radical Cross-Dehydrogenative Coupling.

Chemodivergent synthesis of indeno[1,2-]indoles and isoindolo[2,1-]indoles from the same starting materials involving radical cross-dehydrogenative couplings have been developed. Mn(OAc)·2HO selectively promoted an intramolecular radical C-H/C-H dehydrogenative coupling reaction to provide indeno[1,2-]indoles, while an intramolecular radical C-H/N-H dehydrogenative coupling reaction could proceed via electrochemistry to deliver isoindolo[2,1-]indoles. Plausible mechanisms of the chemodivergent reactions were proposed.

Scalable Electrochemical Aerobic Oxygenation of Indoles to Isatins without Electron Transfer Mediators by Merging with an Oxygen Reduction Reaction.

An approach to electrochemical oxygenation of indoles leading to isatins was developed by merging with a complementary cathode oxygen reduction reaction. The features of this green protocol include the use of molecular oxygen as the sole oxidant, it being free of an electron transfer mediator, and gram-scale preparation. Mechanistic studies suggested a radical process, and the two oxygen atoms in the isatins were both most likely from molecular oxygen.

The Influence of Perceived Red Tape on Public Employees' Procrastination: The Conservation of Resource Theory Perspective.

Procrastination is a prevalent phenomenon in organizations, yet limited knowledge is available on how situational antecedents influence it. Based on the conservation of resource theory, we explore how and when perceived red tape influences public sector employees' procrastination behavior. Using survey data of 751 public sector employees from China, we revealed that perceived red tape is positively associated with procrastination behavior, and role overload partially mediates the relationship between perceived red tape and procrastination behavior.

The Relationship Between Perceived Leader Busyness and Perspective Taking and Interaction Behavior of Followers.

How leaders influence followers have been a hot topic in both research and practice. Yet, prior studies have primarily focused on the impact of one leadership style, while overlooking how a leadership role may influence behavioral expressions of leaders. Particularly, being a leader means having to face time demands and workload pressure, and thus, busyness becomes a common phenomenon for leaders.

Synthesis of Indole-Fused Six-, Seven-, or Eight-Membered N,O-Heterocycles via Rhodium-Catalyzed -Indole-Directed C-H Acetoxylation/Hydrolysis/Annulation.

We report herein the facile synthesis of indole-fused six-, seven-, or eight-membered N,O-heterocycles through rhodium-catalyzed C-H acetoxylation/hydrolysis/annulation. The notable features of this method include C-H acetoxylation using -indole as the intrinsic directing group, high functional group compatibility, and construction of indole-fused medium-sized rings.

Rhodium-Catalyzed Oxidative Annulation of 2- or 7-Arylindoles with Alkenes/Alkynes Using Molecular Oxygen as the Sole Oxidant Enabled by Quaternary Ammonium Salt.

Developing an efficient catalytic system using molecular oxygen as the oxidant for rhodium-catalyzed cross-dehydrogenative coupling remains highly desirable. Herein, rhodium-catalyzed oxidative annulation of 2- or 7-phenyl-1-indoles with alkenes or alkynes to assemble valuable 6-isoindolo[2,1-]indoles, pyrrolo[3,2,1-]phenanthridines, or indolo[2,1-]isoquinolines using the atmospheric pressure of air as the sole oxidant enabled by quaternary ammonium salt has been accomplished. Mechanistic studies provided evidence for the fast intramolecular aza-Michael reaction and aerobic reoxidation of Rh(I)/Rh(III), facilitated by the addition of quaternary ammonium salt.

An Exploratory Study of Police Officers' Perceptions of Health Risk, Work Stress, and Psychological Distress During the COVID-19 Outbreak in China.

Background: How do the police officers perceive health risk, psychological distress, and work stress during the COVID-19 outbreak in China? This study explores the health risk perception, work stress, and psychological distress of police officers who worked at the front line to implement lockdown measures.

Materials And Methods: We conducted a large-scale field survey ( = 5,611) with police officers sample in the northwestern part of China from February 29 to March 7, 2020. Independent-sample -test and ANOVA were used to analyze whether there are differences in health risk perception, work stress, and psychological distress between different groups.