Dinuclear Tridentate Ru(II) Complex with Strong Near-Infrared Light-Triggered Anticancer Activity.

The design of the dinuclear Ru(II) complex () with strong near-infrared (NIR) absorption properties has been reported for efficient anticancer phototherapy. Under 700 nm LED light excitation, exhibited remarkable synergistic type I/II photosensitization ability and photocatalytic activity toward intracellular biomolecules. showed impressive 700 nm light-triggered anticancer activity under normoxia and hypoxia compared with the clinically used photosensitizer Chlorin e6.

A 700 nm LED Light Activated Ru(II) Complex Destroys Tumor Cytoskeleton via Photosensitization and Photocatalysis.

Photoactivable chemotherapy (PACT) using metallic complexes provides spatiotemporal selectivity over drug activation for targeted anticancer therapy. However, the poor absorption in near-infrared (NIR) light region of most metallic complexes renders tissue penetration challenging. Herein, an NIR light triggered dinuclear photoactivable Ru(II) complex (Ru2) is presented and the antitumor mechanism is comprehensively investigated.

Dual-controlled guest release from coordination cages.

Despite having significant applications in the construction of controlled delivery systems with high anti-interference capability, to our knowledge dual-controlled molecular release has not yet been achieved based on small molecular/supramolecular entities. Herein, we report a dual-controlled release system based on coordination cages, for which releasing the guest from the cage demands synchronously altering the coordinative metal cations and the solvent. The cages, HgL and AgL, are constructed via coordination-driven self-assembly of a corannulene-based ligand.

Ultra-low-loaded Ni-Fe Dimer Anchored to Nitrogen/Oxygen Sites for Boosting Electroreduction of Carbon Dioxide.

Single-atom catalysts (SACs), as a novel emerging category in heterogeneous catalysis, have exhibited superb activity and selectivity within the scope of many catalytic reactions, originating from their nature of atomic dispersion. However, they are not appropriate for more complicated reactions that benefit from multi-metal promotion, such as the carbon dioxide reduction reaction (CO RR). Atomic pair catalysts can provide a synergistic effect to break the intrinsic activity limit.

Structural defects on converted bismuth oxide nanotubes enable highly active electrocatalysis of carbon dioxide reduction.

Formic acid (or formate) is suggested to be one of the most economically viable products from electrochemical carbon dioxide reduction. However, its commercial viability hinges on the development of highly active and selective electrocatalysts. Here we report that structural defects have a profound positive impact on the electrocatalytic performance of bismuth.

Rational Synthesis and Assembly of NiS Nanorods for Enhanced Electrochemical Sodium-Ion Storage.

Even though advocated as the potential low-cost alternatives to current lithium-ion technology, the practical viability of sodium-ion batteries remains illusive and depends on the development of high-performance electrode materials. Very few candidates available at present can simultaneously meet the requirements on capacity, rate capability, and cycle life. Herein, we report a high-temperature solution method to prepare NiS nanorods with uniform sizes.

MoC Nanoparticles Dispersed on Hierarchical Carbon Microflowers for Efficient Electrocatalytic Hydrogen Evolution.

The development of nonprecious metal based electrocatalysts for hydrogen evolution reaction (HER) has received increasing attention over recent years. Previous studies have established MoC as a promising candidate. Nevertheless, its preparation requires high reaction temperature, which more than often causes particle sintering and results in low surface areas.

Ultrasmall and phase-pure WC nanoparticles for efficient electrocatalytic and photoelectrochemical hydrogen evolution.

Earlier research has been primarily focused on WC as one of the most promising earth-abundant electrocatalysts for hydrogen evolution reaction (HER), whereas the other compound in this carbide family-WC-has received far less attention. Our theoretical calculations suggest that such a focus is misplaced and WC is potentially more HER-active than WC. Nevertheless, the preparation of phase pure and sintering-free WC nanostructures represents a formidable challenge.

Ultrathin WS2 nanoflakes as a high-performance electrocatalyst for the hydrogen evolution reaction.

Much has been done to search for highly efficient and inexpensive electrocatalysts for the hydrogen evolution reaction (HER), which is critical to a range of electrochemical and photoelectrochemical processes. A new, high-temperature solution-phase method for the synthesis of ultrathin WS2 nanoflakes is now reported. The resulting product possesses monolayer thickness with dimensions in the nanometer range and abundant edges.

PEG-functionalized iron oxide nanoclusters loaded with chlorin e6 for targeted, NIR light induced, photodynamic therapy.

Magnetic targeting that utilizes a magnetic field to specifically delivery theranostic agents to targeted tumor regions can greatly improve the cancer treatment efficiency. Herein, we load chlorin e6 (Ce6), a widely used PS molecule in PDT, on polyethylene glycol (PEG) functionalized iron oxide nanoclusters (IONCs), obtaining IONC-PEG-Ce6 as a theranostic agent for dual-mode imaging guided and magnetic-targeting enhanced in vivo PDT. Interestingly, after being loaded on PEGylated IONCs, the absorbance/excitation peak of Ce6 shows an obvious red-shift from ~650 nm to ~700 nm, which locates in the NIR region with improved tissue penetration.