Publications by authors named "Qiu-bing Zhang"
Article Synopsis
- The study explored the link between Kv1.3 potassium channels in T-lymphocytes and the NLRP3 inflammasome pathway in hypertensive versus healthy Kazakh individuals.
- Blood samples from 30 hypertensive and 30 healthy participants were analyzed, revealing heightened Kv1.3 channel activity and increased levels of NLRP3-related molecules in hypertensive patients.
- Blocking Kv1.3 channels led to a significant reduction in these inflammatory markers, suggesting that Kv1.3 channel activation may play a critical role in the NLRP3 inflammasome pathway in hypertension.
Inhibitory effects of telmisartan on culture and proliferation of and Kv1.3 potassium channel expression in peripheral blood CD4+ T lymphocytes from Xinjiang Kazakh patients with hypertension.
J Renin Angiotensin Aldosterone Syst
October 2016
Introduction: Activation of T lymphocytes, for which potassium channels are essential, is involved in the development of hypertension. In this study, we explored the inhibitory effects of telmisartan on the culture and proliferation of and Kv1.3 potassium channel expression in peripheral blood CD4 T lymphocytes derived from Xinjiang Kazakh patients with hypertension.
View Article and Find Full Text PDFObjective: To observe the current changes of voltage-dependent potassium channel (Kv1.3 potassium channel) and calcium-activated potassium channel (IKCa1 potassium channel) in peripheral blood T-lymphocyte derived from hypertensive patients of Xinjiang Kazakh.
Methods: Twenty randomly selected untreated Kazakh hypertensive patients and 20 Kazakh healthy subjects from Xinjiang were included in this study.