Inhibits Ovarian Cancer Metastasis by Regulating Cytoskeleton Remodeling via .

Epithelial ovarian cancer is the most lethal gynecological malignant tumor. Although debulking surgery, chemotherapy, and PARP inhibitors have greatly improved survival, the prognosis for patients with advanced EOC without HRD is still poor. , as a cell polarity factor, is involved in maintaining cell polarity and asymmetric cell division.

Survival impact of bowel resection in patients with FIGO stage II-IV ovarian cancer.

Introduction: To compare the effect of bowel resection vs stripping on the clinical outcomes of patients with FIGO II-IV ovarian cancer.

Methods: We retrospectively analyzed patients with FIGO II-IV ovarian cancer who suffered from bowel involvement and underwent cytoreductive surgery between January 2014 and March 2022. Patients' survival was compared by Kaplan-Meier survival analysis and Cox proportional hazards models.

Lymphadenectomy in Primary Fallopian Tube Cancer is Associated with Improved Survival.

Background And Objectives: Primary fallopian tube cancer (PFTC) shares the same diagnostic and management guidelines with epithelial ovarian cancer (EOC). The LION trail raised concerns regarding the role of systematic pelvic and para-aortic lymphadenectomy during debulking surgery. We aimed to evaluate the significance of lymphadenectomy in PFTC survival.