A new study of : with two new species proposed and taxonomic status inferred by phylogenetic methods.

(, ) is a monotypic genus with a previously unknown systematic position. In this report, two new species are proposed, and These new taxa are proposed based on morphological characteristics evident via light microscopy and molecular data. Multi-locus phylogenetic analyses (ITS rDNA, nrLSU rDNA, , and ) show that specimens recently collected in Yunnan Province, China are closely related to .

Morphological Characteristics and Phylogeny Reveal Six New Species in Subgenus () from Yanshan Mountains, North China.

Species of the genus are key components of ectomycorrhizal ecosystems worldwide, some of which are famous edible fungi. Although many new species have been described in China, their diversity in North China is still poorly known. Based on the morphology observation of specimens and molecular phylogenetic analyses, combined with the current classification frame of , six new species of subgenus are proposed from the Yanshan Mountains in northern Beijing and northern Hebei Province of China in this study: viz.

Phylogenetic Position of -Like Endophytes on Bamboos and the Diverse Biosynthesis of Hypocrellin and Hypocrellin Derivatives.

The main active ingredients of the fruiting bodies of and are Hypocrellins, belonging perylenequinones with potential photodynamic activity against cancer and microbial diseases. However, the strains of and do not produce hypocrellins in culture, so resource exploitation of natural products was seriously restricted. In this study, a series of novel -like fungal endophyte strains, with varying sporulation ability and synthesizing diverse secondary metabolites, was isolated from different bamboos.

Species of on bamboos from China.

Twenty-seven isolates associated with asymptomatic tissues of bamboo (Bambusoideae, Gramineae) were isolated from Anhui, Beijing, and Guangxi in China. Based on multilocus (internal transcribed spacer [ITS], glyceraldehyde-3-phosphate dehydrogenase [], chitin synthase [], actin [], beta-tubulin []) phylogenetic analyses and morphological characteristics, three species were distinguished, including two novel species, and , and one known species, , which is a first report for China. These species have hitherto only been discovered on Bambusoideae, indicating that they probably have host preference.

SMYD3-associated pathway is involved in the anti-tumor effects of sulforaphane on gastric carcinoma cells.

Sulforaphane (SFN), a natural compound derived from cruciferous vegetables, has been proved to possess potent anti-cancer activity. SMYD3 is a histone methyltransferase which is closely related to the proliferation and migration of cancer cells. This study showed that SFN could dose-dependently induce cell cycle arrest, stimulate apoptosis, and inhibit proliferation and migration of gastric carcinoma cells.

ATM Signaling Pathway Is Implicated in the SMYD3-mediated Proliferation and Migration of Gastric Cancer Cells.

Purpose: We previously found that the histone methyltransferase suppressor of variegation, enhancer of zeste, trithorax and myeloid-nervy-deformed epidermal autoregulatory factor-1 domain-containing protein 3 (SMYD3) is a potential independent predictive factor or prognostic factor for overall survival in gastric cancer patients, but its roles seem to differ from those in other cancers. Therefore, in this study, the detailed functions of SMYD3 in cell proliferation and migration in gastric cancer were examined.

Materials And Methods: SMYD3 was overexpressed or suppressed by transfection with an expression plasmid or siRNA, and a wound healing migration assay and Transwell assay were performed to detect the migration and invasion ability of gastric cancer cells.

Complete Genome Sequence of CGMCC 8198.

We report the complete genome sequence of CGMCC 8198, a novel probiotic strain isolated from fermented herbage. We have determined the complete genome sequence of strain CGMCC 8198, which consists of genes that are likely to be involved in dairy fermentation and that have probiotic qualities.

Ethanol extract of Zhongtian hawthorn lowers serum cholesterol in mice by inhibiting transcription of 3-hydroxy-3-methylglutaryl-CoA reductase via nuclear factor-kappa B signal pathway.

Hawthorn is a berry-like fruit from the species of Crataegus. In China, it has another more famous name, Shan-Zha, which has been used to improve digestion as a traditional Chinese medicine or food for thousands of years. Moreover, during the last decades, hawthorn has received more attention because of its potential to treat cardiovascular diseases.