Total saponins from Panax japonicus attenuate acute alcoholic liver oxidative stress and hepatosteatosis by p62-related Nrf2 pathway and AMPK-ACC/PPARα axis in vivo and in vitro.

Ethnopharmacological Relevance: Panax japonicus (T. Nees) C.A.

Biflavonoids from the twigs and leaves of Mast. and their -glucosidase inhibitory activity.

Three new biflavonoids, umcephabiovins C - E (), along with fourteen known compounds were isolated from the twigs and leaves of . Their structures and configurations were elucidated by UV, IR, NMR, ECD, and HR-ESI-MS spectra. Compounds exhibited significant -glucosidase inhibitory activity with IC values of 7.

A Novel Strategy for Quantitative Analysis of Major Ginsenosides in Panacis Japonici Rhizoma with a Standardized Reference Fraction.

Panacis Japonici Rhizoma (Zhu-Jie-Shen in Chinese), the root of C.A. Mey.

Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells.

Background: Panacis Japonici Rhizoma (PJR) is one of the most famous Chinese medical herbs that is known for exhibiting potential anti-cancer effects.

Purpose: This study aims to isolate and investigate the anti-cancer potential of saponins from PJR in ovarian cancer cells.

Methods: The compounds were separated by comprehensive chromatographic methods.