Anti-inflammatory effects of rosmarinic acid-4-O-β-D-glucoside in reducing acute lung injury in mice infected with influenza virus.

Rosmarinic acid-4-O-β-D-glucoside (RAG) is a dicaffeoyl phenolic compound isolated from Sarcandra glabra (Thunb.) Nakai. Preliminary studies show that RAG has significant anti-inflammatory properties and can alleviate ear swelling in mice and the paw swelling in rats.

The roots of Ilex asprella extract lessens acute respiratory distress syndrome in mice induced by influenza virus.

Ethnopharmacological Relevance: In traditional Chinese medicine, the root of Ilex asprella (Hook. & Arn.) Champ.